Investigator, Howard Hughes Medical Institute
Department Head, Molecular Physiology and Biophysics
Roy J. and Lucille A. Carver Biomedical Research Chair, Molecular Physiology and Biophysics
Professor, Neurology and Internal Medicine
Director, Senator Paul D. Wellstone Muscular Dystrophy Cooperative Research Center (MDCRC)
B.S. (1973) – Manhattan College, Bronx, NY (Physics)
M.S. (1973) – University of Rochester, Rochester, NY (Biophysics)
Ph.D. (1979) – University of Rochester, Rochester, NY (Biophysics)
Postdoctoral Fellow (1981) – University of Toronto, Toronto, Canada (Membrane Biochemistry)
Kevin Campbell, who joined the University of Iowa faculty in 1981, is internationally known for his neuromuscular disease research and directs the Wellstone Muscular Dystrophy Cooperative Research Center at the University of Iowa. Campbell also is a professor of internal medicine and neurology.
Campbell’s work has led to the identification of the molecular and genetic basis of several forms of muscular dystrophy and provided a clearer understanding of muscular dystrophy disease processes. Campbell’s findings have already greatly improved the diagnosis of muscular dystrophy and point to strategies for developing therapies for these devastating inherited neuromuscular diseases.
"Our laboratory's early studies a the University of Iowa focused on elucidating the structure and function of calcium channels in skeletal muscle. For the past twenty years, however, we have actively investigated the molecular pathogenesis of muscular dystrophy. Our laboratory has used biochemical, cell biological, genetic and physiological techniques to identify and define disease mechanisms that cause various forms of muscular dystrophy. In doing so, we cloned and characterized dystroglycan, and demonstrated that it links the cytoskeleton to the extracellular matrix in skeletal muscle. Our studies on dystroglycancell membrane integrity and its role in the molecular pathogenesis of glycosylation-deficient”