Mark T. Keating, M.D.

Mark T. Keating, M.D.

Vice President and Global Head of Cardiovascular and Metabolic Diseases, Novartis Institutes for BioMedical Research, Inc.


A.B. (1976) - Princeton University (Biology)

M.D. (1980) - The Johns Hopkins University, School of Medicine

Internship/Residency - The Johns Hopkins Hospital (Medicine)

Fellowship - University of California, San Francisco (Cardiology)


Mark Keating was born in Fort Hood, Texas and raised in the New Jersey suburb of Manhattan.  He graduated from Princeton (A.B. Biology, 1976) and Johns Hopkins (M.D., 1980), and completed his internship and residency in Internal Medicine at Johns Hopkins Hospital (1980-1983).  Keating then completed a Cardiology fellowship (1983-1985) and a postdoctoral research fellowship with Lewis T. Williams (1985-1989) at UCSF.  He began his independent laboratory as a faculty member in the Departments of Human Genetics, Medicine and Pediatrics (1989-2000) and the Howard Hughes Medical Institute (1994-2000) at the University of Utah.  There Keating focused on the molecular genetics and physiology of cardiovascular disease.  His laboratory did pioneering work on long QT syndrome (LQTS), discovering LQTS genes such as HERG and the first HERG assay, and also developed the diagnostic test for Williams Syndrome.  Keating moved his laboratory to the Howard Hughes Medical Institute and the Departments of Cell Biology and Pediatrics at Harvard Medical School and Children’s Hospital (2000-2005).  His work at Harvard focused on developing zebrafish as a molecular genetic model for studying regeneration, particularly cardiac regeneration.  In 2001, Keating co-founded Hydra Biosciences, a venture-backed biotechnology company in Cambridge, Massachusetts.  Keating joined Novartis in 2005, founding the Department of Ophthalmology.  His group created an innovative pipeline aimed at atherosclerosis, diabetes, and inherited disorders.  Keating was elected to the National Academy of Sciences in 2004 and the American Academy of Arts and Sciences in 2006.