Leon Hess Professor, The Rockefeller University
Director, Anderson Center for Cancer Research
Ph.D. (1981) – University of Amsterdam and The Netherlands Cancer Institute, Amsterdam(Biochemistry)
University of Amsterdam and NIMR, Mill Hill, UK
Postdoctoral Fellowship - University of California, San Francisco
Dr. de Lange earned her Ph.D. in biochemistry from the University of Amsterdam and the Netherlands Cancer Institute in 1985. From 1985 to 1990 she was a postdoctoral fellow in the laboratory of Nobel laureate Harold Varmus at the University of California, San Francisco, where she was one of the first to isolate the telomeres of human chromosomes.
Telomeres are highly specialized DNA-protein structures that cap the ends of linear chromosomes, protecting them from degradation. Impaired functioning of telomeres can lead to genomic instability, and so to cancer, as well as accelerate the aging process
s Anderson Center for Cancer Research. Sir Paul Nurse, Nobel laureate, and Marc Tessier-Lavigne, Ph.D., president of Rockefeller University, nominated de Lange for the Vanderbilt Prize in Biomedical Science.
Dr. de Lange is the winner of The 2011 Vanderbilt Prize in Biomedical Science and also the recipient of the 2011 Vilcek Prize in Biomedical Science, the 2010 AACR Clowes Memorial Award, the 2008 Massachusetts General Hospital Cancer Center Prize, the 2005 NIHs Pioneer Award, the 2004 Charlotte Friend Memorial Award from the AACR and the first Paul Marks Prize for Cancer Research, in 2001.
She is an elected member of the Royal Dutch Academy of Sciences, the European Molecular Biology Organization, the American Academy of Arts and Sciences, and a foreign associate of the National Academy of Sciences.