The Biomechanics Lab is located in Medical Center North and supports the research efforts of orthopaedic surgeons, neurosurgeons, their residents, bone biologists, as well as both Chemical and Biomedical Engineering students and faculty. To accommodate the wide variety of research projects, the lab is equipped with state-of-the-art machinery and software.
Biomechanics Lab Team
Jeffry Nyman, PhD
Assistant Professor of Orthopaedic Surgery and Rehabilitation, Biomedial Engineering
Daniel S. Perrien, PhD
Research Assistant Professor of Orthopaedic Surgery and Rehabilitation
Sasidhar Uppuganti, MS
Biomedical Engineer II
Alexander Makowski, MS
Mathilde Granke, PhD
Biomechanics Lab Equipment
MTS Bionix™ 858 Axial Torsional Test System
This full size, floor mounted servo-hydraulic testing system can perform uni- or bi-axial mechanical tests on material samples, implants or specimens using load or displacement control. It can monotonically or dynamically load specimens in compression, tension, flexure, and torsion thereby simulating a variety of physiologic forces and motions. The Bionix Test System is integrated with state-of-the-art MTS, FlexTest® digital controls, powerful MultiPurpose TestWare (MPT) application software and a host of accessory options (attachment fixtures, load cells, extensometer, etc.) that can be configured to fit a wide variety of testing needs.
Instron DynaMight™ 8800 Servohydraulic Test System
This bench-top, low-capacity servohydraulic test system can perform a wide variety of low-cycle and high-cycle fatigue tests, crack propagation and fracture toughness experiments, as well as other quasi-static tests such as 3-pt, 4-pt bending in load or displacement control modes. The system, combined with advanced features of the 8800 digital controller, FastTrack™ Console software, and WaveMaker™ Editor programming software, and other appropriate accessories (grips, clamps, compression platen, load/torsion cells, extensometer, etc.) is ideal for running a variety of static tensile, compression, flexure, peel, tear and friction tests.
ActiveLife BioDent™ Reference Point Indenter System
BioDent is a new instrument for characerizing the ability of hard materials, like bone, to resist indentation. This compact reference point indentation (RPI) device performs microindentation testing at a scale of 200 microns in-vitro and in-vivo. It uses a probe assembly consisting of a reference probe that can penetrate soft tissue above bone and a test probe that is actuated into and out of the tissue using a force control algorithm. The measurement system records the dynamics of the test probe such as Indentation distance increase, Creep, loading-unloading slope, etc. to help characterize the material properties in turn.
Claron Technologies MicronTracker 3D Motion system
MicronTracker is a real-time sub-millimeter optical tracking system which uses real-time stereoscopic vision to detect and track the location and orientation of specially marked objects, called Xpoints (small checkered target regions securely attached to the moving objects). By far its main advantage is that, unlike older generations of trackers, which rely on custom infrared light emission, MicronTracker is fully passive, using computer vision to process standard video images. MicronTracker cameras connect to a PC using standard IEEE-1394 (FireWire) interface. Multiple cameras may be simultaneously activated to create a larger field of measurement and/or reduce line-of-sight interruptions.
Speciment Preparation & Storage:
Well-designed Wet Laboratory space aids specimen handling, preparation and storage while designing research protocols and experiments. It is equipped with several ultra-low temperature freezers and bone cutting tools as shown below.
Freezer Storage Space
• 2no. VWR Scientific General Purpose Laboratory -20°C Top opening chest Freezer.
• 1no. VWR Scientific General Purpose Laboratory -20°C Front opening door Freezer
• Thermo Scientific Revco Plus Series -86°C Ultra-Low Front opening door Freezer.
• Thermo Scientific TSC* Series -86°C Chest Ultra-Low Top opening chest Freezer.
Bone Cutting Equipment
• South-Bay Technology Inc. Model 660 Variable speed Osteotomy Saw.
• Buehler ISOMET Low-speed Bone cutting Saw.
• SKIL 3385 2-Speed BenchTop Saw.
• RIDGID Power tools DP15501 floor model Drill Press.
• JET BD-920W Belt driven Bench Lathe.
Our Research techniques also use several state-of-art imaging tools housed in Vanderbilt University Institute of Imaging Science’s (VUIIS) Center for Small Animal Imaging, and and a Raman confocal microscope (Renishaw) in the Biomedical Photonics Lab.
Micro-Computed Tomography (MicroCT)
The Scanco uCT 40 and uCT 50 systems are X-ray CT scanners designed for ultrahigh-resolution scanning of ex-vivo specimens. Its microfocal X-ray tube operates between 55 and 90 keV, and the scanner can accommodate samples up to 35 mm in diameter and 80 mm in height. The system is equipped with dedicated software for image reconstruction, visualization, and analysis. The analysis software includes a full suite of tools for bone morphometry measurements and finite analysis.
Canon EOS 7D Digital SLR Camera
The EOS 7D is a high-performance, digital SLR camera with a fine-detail CMOS sensor with about 18MP capacity. It also features a powerful Dual DIGIC4 image processor offering a wide range of functionalities.
- Mathworks Matlab Programming Environment
- GraphPad Prism scientific graphing and statistical software
- SolidWorks 3D Computer Aided Design (CAD) support
- National Instruments (NI) LabView graphical interface software
- MicroDicom – Free DICOM image viewer
- Adobe Photoshop CS6 Toolbox
Development and Histology Support
Visit the Histology Lab Webpage