A strong cadre of investigators is interested in cardiovascular pharmacology. Research programs of collaborating faculty span the gamut from single channel biophysics to whole animal and human investigation. Several investigators are clinicians and their activities span from the bench to bedside. Concerted and overlapping approaches are used to address the basis for therapeutic opportunities of diseases such as arrhythmias, hypertension, and atherosclerosis. Important processes in normal and abnormal physiology, such as platelet and endothelial cell function, angiogenesis, and cardiovascular development, are studied with the goal of understanding these processes and revealing novel therapies. Together these investigators address fundamental questions concerning the molecules that form, regulate, and remodel the cardiovascular system.