Primary Faculty/Secondary Faculty

Sachin Patel, Ph.D., M.D.

Associate Professor of Psychiatry and Behavioral Sciences

James G. Blakemore Chair in Psychiatry

Research Description

Psychosocial stress is a key trigger for the development and exacerbation of a variety of psychiatric disorders including depression, addiction, schizophrenia, and post-traumatic stress disorder. By understanding the molecular, structural, and physiological adaptations in endocannabinoid signaling that occur in response to stress, we hope uncover novel bio-markers and pharmacological targets for drug development. In addition, we hope these investigations will provide insight into the pathophysiology of stress-related neuropsychiatric disorders. We use a variety of techniques including electrophysiology, mass spectrometry, protein biochemistry, genetic models, and functional anatomical studies, to understand the role of endocannabinoids in the brain's response to stress.

Clinical Interest

My clinical work focuses on acute inpatient care of patients with dual mood/anxiety disorders and addiction.

Selected Publications