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Ana M D Carneiro, Ph.D.

Assistant Professor of Pharmacology

Research Description

My laboratory studies the molecular mechanisms by which integrins protein complexes influence cell function and behavior. Integrins coordinate cell surface receptors, neurotransmitter transporters and intracellular signaling proteins in a tissue-dependent manner. Therefore, first we need to figure out which signaling networks and proteins are modulated by integrins. We focus on the discovery and characterization of protein-protein interactions through biochemical and proteomic approaches. These findings are then taken to the whole animal, where we generate genetically modified mice or disrupt the protein complexes by pharmacological manipulation and measure the outcome in behavioral studies.

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Vanderbilt Brain Institute (VBI)