Laurence Zwiebel, Ph.D.

Laurence Zwiebel, Ph.D.

Professor of Biological Sciences
Cornelius Vanderbilt Chair, Biological Sciences

: l.zwiebel@vanderbilt.edu
: (615) 343-1894
: 465 21st Ave. South
Nashville, Tennessee - 37235

Selected Publications

Zhou X, Rokas A, Berger SL, Liebig J, Ray A, Zwiebel LJ. Chemoreceptor Evolution in Hymenoptera and Its Implications for the Evolution of Eusociality [letter]. Genome Biol Evol. 2015 Aug; 7(8): 2407-16. PMID: 26272716, PMCID: PMC4558866, PII: evv149, DOI: 10.1093/gbe/evv149, ISSN: 1759-6653.
Neafsey DE, Waterhouse RM, Abai MR, Aganezov SS, Alekseyev MA, Allen JE, Amon J, Arcà B, Arensburger P, Artemov G, Assour LA, Basseri H, Berlin A, Birren BW, Blandin SA, Brockman AI, Burkot TR, Burt A, Chan CS, Chauve C, Chiu JC, Christensen M, Costantini C, Davidson VL, Deligianni E, Dottorini T, Dritsou V, Gabriel SB, Guelbeogo WM, Hall AB, Han MV, Hlaing T, Hughes DS, Jenkins AM, Jiang X, Jungreis I, Kakani EG, Kamali M, Kemppainen P, Kennedy RC, Kirmitzoglou IK, Koekemoer LL, Laban N, Langridge N, Lawniczak MK, Lirakis M, Lobo NF, Lowy E, MacCallum RM, Mao C, Maslen G, Mbogo C, McCarthy J, Michel K, Mitchell SN, Moore W, Murphy KA, Naumenko AN, Nolan T, Novoa EM, O’Loughlin S, Oringanje C, Oshaghi MA, Pakpour N, Papathanos PA, Peery AN, Povelones M, Prakash A, Price DP, Rajaraman A, Reimer LJ, Rinker DC, Rokas A, Russell TL, Sagnon N, Sharakhova MV, Shea T, Simão FA, Simard F, Slotman MA, Somboon P, Stegniy V, Struchiner CJ, Thomas GW, Tojo M, Topalis P, Tubio JM, Unger MF, Vontas J, Walton C, Wilding CS, Willis JH, Wu YC, Yan G, Zdobnov EM, Zhou X, Catteruccia F, Christophides GK, Collins FH, Cornman RS, Crisanti A, Donnelly MJ, Emrich SJ, Fontaine MC, Gelbart W, Hahn MW, Hansen IA, Howell PI, Kafatos FC, Kellis M, Lawson D, Louis C, Luckhart S, Muskavitch MA, Ribeiro JM, Riehle MA, Sharakhov IV, Tu Z, Zwiebel LJ, Besansky NJ. Mosquito genomics. Highly evolvable malaria vectors: the genomes of 16 Anopheles mosquitoes. Science [print-electronic]. 2015 Jan 1/2/2015; 347(6217): 1258522. PMID: 25554792, PMCID: PMC4380271, PII: science.1258522, DOI: 10.1126/science.1258522, ISSN: 1095-9203.
Suh E, Bohbot J, Zwiebel LJ. Peripheral olfactory signaling in insects. Curr Opin Insect Sci. 2014 Dec 12/1/2014; 6: 86-92. PMID: 25584200, PMCID: PMC4288021, DOI: 10.1016/j.cois.2014.10.006, ISSN: 2214-5745.
Turner RM, Derryberry SL, Kumar BN, Brittain T, Zwiebel LJ, Newcomb RD, Christie DL. Mutational analysis of cysteine residues of the insect odorant co-receptor (Orco) from Drosophila melanogaster reveals differential effects on agonist- and odorant-tuning receptor-dependent activation. J. Biol. Chem [print-electronic]. 2014 Nov 11/14/2014; 289(46): 31837-45. PMID: 25271160, PMCID: PMC4231661, PII: M114.603993, DOI: 10.1074/jbc.M114.603993, ISSN: 1083-351X.
Turner RM, Derryberry SL, Kumar BN, Brittain T, Zwiebel LJ, Newcomb RD, Christie DL. Mutational analysis of cysteine residues of the insect odorant co-receptor (Orco) from Drosophila melanogaster reveals differential effects on agonist- and odorant-tuning receptor-dependent activation. J. Biol. Chem [print-electronic]. 2014 Nov 11/14/2014; 289(46): 31837-45. PMID: 25271160, PMCID: PMC4231661, PII: M114.603993, DOI: 10.1074/jbc.M114.603993, ISSN: 1083-351X.
Hughes DT, Wang G, Zwiebel LJ, Luetje CW. A determinant of odorant specificity is located at the extracellular loop 2-transmembrane domain 4 interface of an Anopheles gambiae odorant receptor subunit. Chem. Senses [print-electronic]. 2014 Nov; 39(9): 761-9. PMID: 25270378, PMCID: PMC4201304, PII: bju048, DOI: 10.1093/chemse/bju048, ISSN: 1464-3553.
Hughes DT, Wang G, Zwiebel LJ, Luetje CW. A determinant of odorant specificity is located at the extracellular loop 2-transmembrane domain 4 interface of an Anopheles gambiae odorant receptor subunit. Chem. Senses [print-electronic]. 2014 Nov; 39(9): 761-9. PMID: 25270378, PMCID: PMC4201304, PII: bju048, DOI: 10.1093/chemse/bju048, ISSN: 1464-3553.
Zhou X, Rinker DC, Pitts RJ, Rokas A, Zwiebel LJ. Divergent and conserved elements comprise the chemoreceptive repertoire of the nonblood-feeding mosquito Toxorhynchites amboinensis. Genome Biol Evol. 2014 Oct; 6(10): 2883-96. PMID: 25326137, PMCID: PMC4224357, PII: evu231, DOI: 10.1093/gbe/evu231, ISSN: 1759-6653.
Romaine IM, Taylor RW, Saidu SP, Kim K, Sulikowski GA, Zwiebel LJ, Waterson AG. Narrow SAR in odorant sensing Orco receptor agonists. Bioorg. Med. Chem. Lett [print-electronic]. 2014 Jun 6/15/2014; 24(12): 2613-6. PMID: 24813736, PMCID: PMC4111141, PII: S0960-894X(14)00438-7, DOI: 10.1016/j.bmcl.2014.04.081, ISSN: 1464-3405.
Romaine IM, Taylor RW, Saidu SP, Kim K, Sulikowski GA, Zwiebel LJ, Waterson AG. Narrow SAR in odorant sensing Orco receptor agonists. Bioorg. Med. Chem. Lett [print-electronic]. 2014 Jun 6/15/2014; 24(12): 2613-6. PMID: 24813736, PMCID: PMC4111141, PII: S0960-894X(14)00438-7, DOI: 10.1016/j.bmcl.2014.04.081, ISSN: 1464-3405.
Pitts RJ, Liu C, Zhou X, Malpartida JC, Zwiebel LJ. Odorant receptor-mediated sperm activation in disease vector mosquitoes. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2014 Feb 2/18/2014; 111(7): 2566-71. PMID: 24550284, PMCID: PMC3932880, PII: 1322923111, DOI: 10.1073/pnas.1322923111, ISSN: 1091-6490.
Pitts RJ, Liu C, Zhou X, Malpartida JC, Zwiebel LJ. Odorant receptor-mediated sperm activation in disease vector mosquitoes. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2014 Feb 2/18/2014; 111(7): 2566-71. PMID: 24550284, PMCID: PMC3932880, PII: 1322923111, DOI: 10.1073/pnas.1322923111, ISSN: 1091-6490.
Pitts RJ, Derryberry SL, Pulous FE, Zwiebel LJ. Antennal-expressed ammonium transporters in the malaria vector mosquito Anopheles gambiae. PLoS ONE. 2014; 9(10): e111858. PMID: 25360676, PMCID: PMC4216128, PII: PONE-D-14-20321, DOI: 10.1371/journal.pone.0111858, ISSN: 1932-6203.
Rinker DC, Pitts RJ, Zhou X, Suh E, Rokas A, Zwiebel LJ. Blood meal-induced changes to antennal transcriptome profiles reveal shifts in odor sensitivities in Anopheles gambiae. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2013 May 5/14/2013; 110(20): 8260-5. PMID: 23630291, PMCID: PMC3657813, PII: 1302562110, DOI: 10.1073/pnas.1302562110, ISSN: 1091-6490.
Rinker DC, Pitts RJ, Zhou X, Suh E, Rokas A, Zwiebel LJ. Blood meal-induced changes to antennal transcriptome profiles reveal shifts in odor sensitivities in Anopheles gambiae. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2013 May 5/14/2013; 110(20): 8260-5. PMID: 23630291, PMCID: PMC3657813, PII: 1302562110, DOI: 10.1073/pnas.1302562110, ISSN: 1091-6490.
Pask GM, Bobkov YV, Corey EA, Ache BW, Zwiebel LJ. Blockade of insect odorant receptor currents by amiloride derivatives. Chem. Senses [print-electronic]. 2013 Mar; 38(3): 221-9. PMID: 23292750, PMCID: PMC3569625, PII: bjs100, DOI: 10.1093/chemse/bjs100, ISSN: 1464-3553.
Liu C, Zwiebel LJ. Molecular characterization of larval peripheral thermosensory responses of the malaria vector mosquito Anopheles gambiae. PLoS ONE [electronic-print]. 2013; 8(8): e72595. PMID: 23940815, PMCID: PMC3737131, PII: PONE-D-13-23760, DOI: 10.1371/journal.pone.0072595, ISSN: 1932-6203.
Liu C, Zwiebel LJ. Molecular characterization of larval peripheral thermosensory responses of the malaria vector mosquito Anopheles gambiae. PLoS ONE [electronic-print]. 2013; 8(8): e72595. PMID: 23940815, PMCID: PMC3737131, PII: PONE-D-13-23760, DOI: 10.1371/journal.pone.0072595, ISSN: 1932-6203.
Pask GM, Romaine IM, Zwiebel LJ. The molecular receptive range of a lactone receptor in Anopheles gambiae. Chem. Senses [print-electronic]. 2013 Jan; 38(1): 19-25. PMID: 22944613, PMCID: PMC3522515, PII: bjs074, DOI: 10.1093/chemse/bjs074, ISSN: 1464-3553.
Rinker DC, Zhou X, Pitts RJ, , Rokas A, Zwiebel LJ. Antennal transcriptome profiles of anopheline mosquitoes reveal human host olfactory specialization in Anopheles gambiae. BMC Genomics. 2013; 14: 749. PMID: 24182346, PMCID: PMC3833343, PII: 1471-2164-14-749, DOI: 10.1186/1471-2164-14-749, ISSN: 1471-2164.
Rinker DC, Zhou X, Pitts RJ, , Rokas A, Zwiebel LJ. Antennal transcriptome profiles of anopheline mosquitoes reveal human host olfactory specialization in Anopheles gambiae. BMC Genomics. 2013; 14: 749. PMID: 24182346, PMCID: PMC3833343, PII: 1471-2164-14-749, DOI: 10.1186/1471-2164-14-749, ISSN: 1471-2164.
Taylor RW, Romaine IM, Liu C, Murthi P, Jones PL, Waterson AG, Sulikowski GA, Zwiebel LJ. Structure-activity relationship of a broad-spectrum insect odorant receptor agonist. ACS Chem. Biol [print-electronic]. 2012 Oct 10/19/2012; 7(10): 1647-52. PMID: 22924767, DOI: 10.1021/cb300331z, ISSN: 1554-8937.
Jones PL, Pask GM, Romaine IM, Taylor RW, Reid PR, Waterson AG, Sulikowski GA, Zwiebel LJ. Allosteric antagonism of insect odorant receptor ion channels. PLoS ONE [print-electronic]. 2012; 7(1): e30304. PMID: 22272331, PMCID: PMC3260273, PII: PONE-D-11-19400, DOI: 10.1371/journal.pone.0030304, ISSN: 1932-6203.
Zhou X, Slone JD, Rokas A, Berger SL, Liebig J, Ray A, Reinberg D, Zwiebel LJ. Phylogenetic and transcriptomic analysis of chemosensory receptors in a pair of divergent ant species reveals sex-specific signatures of odor coding. PLoS Genet [print-electronic]. 2012; 8(8): e1002930. PMID: 22952454, PMCID: PMC3431598, PII: PGENETICS-D-12-00741, DOI: 10.1371/journal.pgen.1002930, ISSN: 1553-7404.
Jones PL, Pask GM, Rinker DC, Zwiebel LJ. Functional agonism of insect odorant receptor ion channels. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2011 May 5/24/2011; 108(21): 8821-5. PMID: 21555561, PMCID: PMC3102409, PII: 1102425108, DOI: 10.1073/pnas.1102425108, ISSN: 1091-6490.
Bohbot JD, Jones PL, Wang G, Pitts RJ, Pask GM, Zwiebel LJ. Conservation of indole responsive odorant receptors in mosquitoes reveals an ancient olfactory trait. Chem. Senses [print-electronic]. 2011 Jan; 36(2): 149-60. PMID: 20956733, PMCID: PMC3020388, PII: bjq105, DOI: 10.1093/chemse/bjq105, ISSN: 1464-3553.
Pask GM, Jones PL, Rützler M, Rinker DC, Zwiebel LJ. Heteromeric Anopheline odorant receptors exhibit distinct channel properties. PLoS ONE [print-electronic]. 2011; 6(12): e28774. PMID: 22174894, PMCID: PMC3235152, PII: PONE-D-11-18890, DOI: 10.1371/journal.pone.0028774, ISSN: 1932-6203.
Pitts RJ, Rinker DC, Jones PL, Rokas A, Zwiebel LJ. Transcriptome profiling of chemosensory appendages in the malaria vector Anopheles gambiae reveals tissue- and sex-specific signatures of odor coding. BMC Genomics. 2011; 12: 271. PMID: 21619637, PMCID: PMC3126782, PII: 1471-2164-12-271, DOI: 10.1186/1471-2164-12-271, ISSN: 1471-2164.
Carey AF, Wang G, Su CY, Zwiebel LJ, Carlson JR. Odorant reception in the malaria mosquito Anopheles gambiae. Nature [print-electronic]. 2010 Mar 3/4/2010; 464(7285): 66-71. PMID: 20130575, PMCID: PMC2833235, PII: nature08834, DOI: 10.1038/nature08834, ISSN: 1476-4687.
Wang G, Carey AF, Carlson JR, Zwiebel LJ. Molecular basis of odor coding in the malaria vector mosquito Anopheles gambiae. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2010 Mar 3/2/2010; 107(9): 4418-23. PMID: 20160092, PMCID: PMC2840125, PII: 0913392107, DOI: 10.1073/pnas.0913392107, ISSN: 1091-6490.
Liu C, Pitts RJ, Bohbot JD, Jones PL, Wang G, Zwiebel LJ. Distinct olfactory signaling mechanisms in the malaria vector mosquito Anopheles gambiae. PLoS Biol. 2010; 8(8): PMID: 20824161, PMCID: PMC2930861, DOI: 10.1371/journal.pbio.1000467, ISSN: 1545-7885.
Wang G, Qiu YT, Lu T, Kwon HW, Pitts RJ, Van Loon JJ, Takken W, Zwiebel LJ. Anopheles gambiae TRPA1 is a heat-activated channel expressed in thermosensitive sensilla of female antennae. Eur. J. Neurosci [print-electronic]. 2009 Sep; 30(6): 967-74. PMID: 19735290, PMCID: PMC3106298, PII: EJN6901, DOI: 10.1111/j.1460-9568.2009.06901.x, ISSN: 1460-9568.
Xia Y, Wang G, Buscariollo D, Pitts RJ, Wenger H, Zwiebel LJ. The molecular and cellular basis of olfactory-driven behavior in Anopheles gambiae larvae. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2008 Apr 4/29/2008; 105(17): 6433-8. PMID: 18427108, PMCID: PMC2359781, PII: 0801007105, DOI: 10.1073/pnas.0801007105, ISSN: 1091-6490.
Walker WB, Smith EM, Jan T, Zwiebel LJ. A functional role for Anopheles gambiae Arrestin1 in olfactory signal transduction. J. Insect Physiol [print-electronic]. 2008 Apr; 54(4): 680-90. PMID: 18328499, PMCID: PMC2408752, PII: S0022-1910(08)00022-X, DOI: 10.1016/j.jinsphys.2008.01.007, ISSN: 0022-1910.
Bohbot J, Pitts RJ, Kwon HW, Rützler M, Robertson HM, Zwiebel LJ. Molecular characterization of the Aedes aegypti odorant receptor gene family. Insect Mol. Biol [print-electronic]. 2007 Oct; 16(5): 525-37. PMID: 17635615, PMCID: PMC3100214, PII: IMB748, DOI: 10.1111/j.1365-2583.2007.00748.x, ISSN: 0962-1075.
Lu T, Qiu YT, Wang G, Kwon JY, Rutzler M, Kwon HW, Pitts RJ, van Loon JJ, Takken W, Carlson JR, Zwiebel LJ. Odor coding in the maxillary palp of the malaria vector mosquito Anopheles gambiae. Curr. Biol [print-electronic]. 2007 Sep 9/18/2007; 17(18): 1533-44. PMID: 17764944, PMCID: PMC3113458, PII: S0960-9822(07)01780-0, DOI: 10.1016/j.cub.2007.07.062, ISSN: 0960-9822.
Rützler M, Lu T, Zwiebel LJ. Galpha encoding gene family of the malaria vector mosquito Anopheles gambiae: expression analysis and immunolocalization of AGalphaq and AGalphao in female antennae. J. Comp. Neurol. 2006 Dec 12/1/2006; 499(4): 533-45. PMID: 17029251, PMCID: PMC3113460, DOI: 10.1002/cne.21083, ISSN: 0021-9967.
Kwon HW, Lu T, Rützler M, Zwiebel LJ. Olfactory responses in a gustatory organ of the malaria vector mosquito Anopheles gambiae. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2006 Sep 9/5/2006; 103(36): 13526-31. PMID: 16938890, PMCID: PMC1569196, PII: 0601107103, DOI: 10.1073/pnas.0601107103, ISSN: 0027-8424.
Xia Y, Zwiebel LJ. Identification and characterization of an odorant receptor from the West Nile virus mosquito, Culex quinquefasciatus. Insect Biochem. Mol. Biol [print-electronic]. 2006 Mar; 36(3): 169-76. PMID: 16503478, PMCID: PMC3100213, PII: S0965-1748(05)00225-0, DOI: 10.1016/j.ibmb.2005.12.003, ISSN: 0965-1748.
Pitts RJ, Zwiebel LJ. Antennal sensilla of two female anopheline sibling species with differing host ranges. Malar. J. 2006; 5: 26. PMID: 16573828, PMCID: PMC1532926, PII: 1475-2875-5-26, DOI: 10.1186/1475-2875-5-26, ISSN: 1475-2875.
Rützler M, Zwiebel LJ. Molecular biology of insect olfaction: recent progress and conceptual models. J. Comp. Physiol. A Neuroethol. Sens. Neural. Behav. Physiol [print-electronic]. 2005 Sep; 191(9): 777-90. PMID: 16094545, DOI: 10.1007/s00359-005-0044-y, ISSN: 0340-7594.
Merrill CE, Sherertz TM, Walker WB, Zwiebel LJ. Odorant-specific requirements for arrestin function in Drosophila olfaction. J. Neurobiol. 2005 Apr; 63(1): 15-28. PMID: 15627264, DOI: 10.1002/neu.20113, ISSN: 0022-3034.
Zwiebel LJ, Takken W. Olfactory regulation of mosquito-host interactions. Insect Biochem. Mol. Biol. 2004 Jul; 34(7): 645-52. PMID: 15242705, PMCID: PMC3100215, PII: S0965174804000682, DOI: 10.1016/j.ibmb.2004.03.017, ISSN: 0965-1748.
Melo AC, Rützler M, Pitts RJ, Zwiebel LJ. Identification of a chemosensory receptor from the yellow fever mosquito, Aedes aegypti, that is highly conserved and expressed in olfactory and gustatory organs. Chem. Senses. 2004 Jun; 29(5): 403-10. PMID: 15201207, PII: 29/5/403, DOI: 10.1093/chemse/bjh041, ISSN: 0379-864X.
Pitts RJ, Fox AN, Zwiebel LJ. A highly conserved candidate chemoreceptor expressed in both olfactory and gustatory tissues in the malaria vector Anopheles gambiae. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2004 Apr 4/6/2004; 101(14): 5058-63. PMID: 15037749, PMCID: PMC387373, PII: 0308146101, DOI: 10.1073/pnas.0308146101, ISSN: 0027-8424.
Hallem EA, Nicole Fox A, Zwiebel LJ, Carlson JR. Olfaction: mosquito receptor for human-sweat odorant. Nature. 2004 Jan 1/15/2004; 427(6971): 212-3. PMID: 14724626, PII: 427212a, DOI: 10.1038/427212a, ISSN: 1476-4687.
Merrill CE, Pitts RJ, Zwiebel LJ. Molecular characterization of arrestin family members in the malaria vector mosquito, Anopheles gambiae. Insect Mol. Biol. 2003 Dec; 12(6): 641-50. PMID: 14986925, ISSN: 0962-1075.
Xu PX, Zwiebel LJ, Smith DP. Identification of a distinct family of genes encoding atypical odorant-binding proteins in the malaria vector mosquito, Anopheles gambiae. Insect Mol. Biol. 2003 Dec; 12(6): 549-60. PMID: 14986916, ISSN: 0962-1075.
Hill CA, Fox AN, Pitts RJ, Kent LB, Tan PL, Chrystal MA, Cravchik A, Collins FH, Robertson HM, Zwiebel LJ. G protein-coupled receptors in Anopheles gambiae. Science. 2002 Oct 10/4/2002; 298(5591): 176-8. PMID: 12364795, PII: 298/5591/176, DOI: 10.1126/science.1076196, ISSN: 1095-9203.
Fox AN, Pitts RJ, Zwiebel LJ. A cluster of candidate odorant receptors from the malaria vector mosquito, Anopheles gambiae. Chem. Senses. 2002 Jun; 27(5): 453-9. PMID: 12052782, ISSN: 0379-864X.
Merrill CE, Riesgo-Escovar J, Pitts RJ, Kafatos FC, Carlson JR, Zwiebel LJ. Visual arrestins in olfactory pathways of Drosophila and the malaria vector mosquito Anopheles gambiae. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2002 Feb 2/5/2002; 99(3): 1633-8. PMID: 11792843, PMCID: PMC122242, PII: 022505499, DOI: 10.1073/pnas.022505499, ISSN: 0027-8424.
Fox AN, Pitts RJ, Robertson HM, Carlson JR, Zwiebel LJ. Candidate odorant receptors from the malaria vector mosquito Anopheles gambiae and evidence of down-regulation in response to blood feeding. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2001 Dec 12/4/2001; 98(25): 14693-7. PMID: 11724964, PMCID: PMC64743, PII: 261432998, DOI: 10.1073/pnas.261432998, ISSN: 0027-8424.
Pitts RJ, Zwiebel LJ. Isolation and characterization of the Xanthine dehydrogenase gene of the Mediterranean fruit fly, Ceratitis capitata. Genetics. 2001 Aug; 158(4): 1645-55. PMID: 11514452, PMCID: PMC1461762, ISSN: 0016-6731.
Gomulski LM, Pitts RJ, Costa S, Saccone G, Torti C, Polito LC, Gasperi G, Malacrida AR, Kafatos FC, Zwiebel LJ. Genomic organization and characterization of the white locus of the Mediterranean fruitfly, Ceratitis capitata. Genetics. 2001 Mar; 157(3): 1245-55. PMID: 11238408, PMCID: PMC1461546, ISSN: 0016-6731.
Zwiebel LJ, Saccone G, Zacharopoulou A, Besansky NJ, Favia G, Collins FH, Louis C, Kafatos FC. The white gene of Ceratitis capitata: a phenotypic marker for germline transformation. Science. 1995 Dec 12/22/1995; 270(5244): 2005-8. PMID: 8533095, ISSN: 0036-8075.
Edery I, Zwiebel LJ, Dembinska ME, Rosbash M. Temporal phosphorylation of the Drosophila period protein. Proc. Natl. Acad. Sci. U.S.A. 1994 Mar 3/15/1994; 91(6): 2260-4. PMID: 8134384, PMCID: PMC43350, ISSN: 0027-8424.
Liu X, Zwiebel LJ, Hinton D, Benzer S, Hall JC, Rosbash M. The period gene encodes a predominantly nuclear protein in adult Drosophila. J. Neurosci. 1992 Jul; 12(7): 2735-44. PMID: 1613555, ISSN: 0270-6474.
Zwiebel LJ, Hardin PE, Liu X, Hall JC, Rosbash M. A post-transcriptional mechanism contributes to circadian cycling of a per-beta-galactosidase fusion protein. Proc. Natl. Acad. Sci. U.S.A. 1991 May 5/1/1991; 88(9): 3882-6. PMID: 1902573, PMCID: PMC51557, ISSN: 0027-8424.
Liu X, Yu QA, Huang ZS, Zwiebel LJ, Hall JC, Rosbash M. The strength and periodicity of D. melanogaster circadian rhythms are differentially affected by alterations in period gene expression. Neuron. 1991 May; 6(5): 753-66. PMID: 1902699, PII: 0896-6273(91)90172-V, ISSN: 0896-6273.
Zwiebel LJ, Hardin PE, Hall JC, Rosbash M. Circadian oscillations in protein and mRNA levels of the period gene of Drosophila melanogaster. Biochem. Soc. Trans. 1991 Apr; 19(2): 533-7. PMID: 1909668, ISSN: 0300-5127.
Hamblen-Coyle M, Konopka RJ, Zwiebel LJ, Colot HV, Dowse HB, Rosbash M, Hall JC. A new mutation at the period locus of Drosophila melanogaster with some novel effects on circadian rhythms. J. Neurogenet. 1989 Aug; 5(4): 229-56. PMID: 2509652, ISSN: 0167-7063.
Hamblen M, Zehring WA, Kyriacou CP, Reddy P, Yu Q, Wheeler DA, Zwiebel LJ, Konopka RJ, Rosbash M, Hall JC. Germ-line transformation involving DNA from the period locus in Drosophila melanogaster: overlapping genomic fragments that restore circadian and ultradian rhythmicity to per0 and per- mutants. J. Neurogenet. 1986 Sep; 3(5): 249-91. PMID: 3097289, ISSN: 0167-7063.
Zwiebel LJ, Cohn VH, Wright DR, Moore GP. Evolution of single-copy DNA and the ADH gene in seven drosophilids. J. Mol. Evol. 1982; 19(1): 62-71. PMID: 6761443, ISSN: 0022-2844.
Zwiebel LJ, Inukai M, Nakamura K, Inouye M. Preferential selection of deletion mutations of the outer membrane lipoprotein gene of Escherichia coli by globomycin. J. Bacteriol. 1981 Jan; 145(1): 654-6. PMID: 7007330, PMCID: PMC217321, ISSN: 0021-9193.