Graduate Student, V. Gurevich and Iverson laboratories
BS and BA, Wittenburg University (2014)
Nicki is under the co-mentorship of Dr. Gurevich and Dr. Iverson, whose labs she officially joined in April 2015. Her chosen thesis research, which is to elucidate the interaction of arrestin-3 with the mitogen-activated protein kinases (MAPKs), is based on evidence from both labs and current publications in the field. As a member of two labs, Nicki is presented with the unique opportunity to approach her scientific questions from two angles: biochemical assays, which allow her to conduct studies of arrestin function, and macromolecular X-ray crystallography, which she uses to determine different arrestin complex structures. This arrangement enables her to develop novel functional experiments with the help of solved crystal structures, a process that usually requires extensive collaboration. It also exposes her to a wide variety of experimental techniques, which range from basic molecular and cell biology to advanced instrumental study.