Primary Faculty

Peter R. Martin, M.D.

Professor of Psychiatry and Behavioral Sciences
Professor of Pharmacology

M.Sc., University of Toronto (Pharmacology)
M.D., McGill University (Medicine)
B.Sc., McGill University (Honours Molecular Genetics)

Brief Bio
Dr. Peter Martin has been a member of the faculty since 1986, when he established the Division of Addiction Psychiatry. His research and scholarly interests include the molecular basis, diagnosis, and treatment of drug use disorders with an emphasis on substance-induced mental disorders.

Clinical Interests
Addiction Psychiatry, General Psychiatry, Psychopharmacology, Neuropsychiatry

Research Interests
Molecular biology of thiamine, neuroimaging to elucidate the pathogenesis of addiction and alcohol-induced brain damage, and the clinical pharmacology of addictive substances, including novel pharmacological treatments of addictive disorders and treatment of opioid use disorder during pregnancy.

Representative publications

  1. Gorodetzky Charles W, Walsh Sharon L, Martin Peter R, Saxon Andrew J, Gullo Kristen L, Biswas Kousick. A phase III, randomized, multi-center, double blind, placebo controlled study of safety and efficacy of lofexidine for relief of symptoms in individuals undergoing inpatient opioid withdrawal. Drug and alcohol dependence 2017 May;176: PMID: 28527421.
  2. Lima Juliana de Paula, Farah Adriana, King Benjamin, de Paulis Tomas, Martin Peter R. Distribution of Major Chlorogenic Acids and Related Compounds in Brazilian Green and Toasted Ilex paraguariensis (Maté) Leaves. Journal of agricultural and food chemistry 2016 Mar;64(11) PMID: 26924157.
  3. Patrick Stephen W, Dudley Judith, Martin Peter R, Harrell Frank E, Warren Michael D, Hartmann Katherine E, Ely E Wesley, Grijalva Carlos G, Cooper William O. Prescription opioid epidemic and infant outcomes. Pediatrics 2015 May;135(5) PMID: 25869370 PMCID: PMC4411781.
  4. Martin Peter R, Finlayson A J Reid. Opioid use disorder during pregnancy in Tennessee: expediency vs. science. The American journal of drug and alcohol abuse 2015; 41(5) PMID: 26186388.
  5. Iannelli Richard J, Finlayson A J Reid, Brown Kimberly P, Neufeld Ron, Gray Roland, Dietrich Mary S, Martin Peter R. Suicidal behavior among physicians referred for fitness-for-duty evaluation. General hospital psychiatry 2014 Nov;36(6) PMID: 25085717 PMCID: PMC4254198.
  6. Ferri Michael, Finlayson Alistair J Reid, Wang Li, Martin Peter R. Predictive factors for relapse in patients on buprenorphine maintenance. The American journal on addictions 2014 Jan;23(1) PMID: 24313243 PMCID: PMC3922612.
  7. Benningfield Margaret M, Blackford Jennifer U, Ellsworth Melissa E, Samanez-Larkin Gregory R, Martin Peter R, Cowan Ronald L, Zald David H. Caudate responses to reward anticipation associated with delay discounting behavior in healthy youth. Developmental cognitive neuroscience 2014 Jan;7: PMID: 24309299 PMCID: PMC3932556.
  8. Stephen Rich J, Martin Peter R. Co-occurring psychiatric disorders and alcoholism. Handbook of clinical neurology 2014; 125: PMID: 25307597.
  9. Finlayson A J Reid, Dietrich Mary S, Neufeld Ron, Roback Howard, Martin Peter R. Restoring professionalism: the physician fitness-for-duty evaluation. General hospital psychiatry 2013 Nov;35(6) PMID: 23910216 PMCID: PMC3923266.
  10. Charboneau Evonne J, Dietrich Mary S, Park Sohee, Cao Aize, Watkins Tristan J, Blackford Jennifer U, Benningfield Margaret M, Martin Peter R, Buchowski Maciej S, Cowan Ronald L. Cannabis cue-induced brain activation correlates with drug craving in limbic and visual salience regions: preliminary results. Psychiatry research 2013 Nov;214(2) PMID: 24035535 PMCID: PMC3904759.
  11. Epstein Richard A, Bobo William V, Martin Peter R, Morrow James A, Wang Wei, Chandrasekhar Rameela, Cooper William O. Increasing pregnancy-related use of prescribed opioid analgesics. Annals of epidemiology 2013 Aug;23(8) PMID: 23889859 PMCID: PMC3888316.
  12. Jackson Tracy P, Lonergan Daniel F, Todd R David, Martin Peter R. Intentional intrathecal opioid detoxification in 3 patients: characterization of the intrathecal opioid withdrawal syndrome. Pain practice : the official journal of World Institute of Pain 2013 Apr;13(4) PMID: 22925591.
  13. Benningfield Margaret M, Dietrich Mary S, Jones Hendrée E, Kaltenbach Karol, Heil Sarah H, Stine Susan M, Coyle Mara G, Arria Amelia M, O'Grady Kevin E, Fischer Gabriele, Martin Peter R. Opioid dependence during pregnancy: relationships of anxiety and depression symptoms to treatment outcomes. Addiction (Abingdon, England) 2012 Nov;107 Suppl 1: PMID: 23106929 PMCID: PMC4315620.
  14. Young Jessica L, Martin Peter R. Treatment of opioid dependence in the setting of pregnancy. The Psychiatric clinics of North America 2012 Jun;35(2) PMID: 22640765.
  15. Rogers Baxter P, Parks Mitchell H, Nickel Mark K, Katwal Santosh B, Martin Peter R. Reduced fronto-cerebellar functional connectivity in chronic alcoholic patients. Alcoholism, clinical and experimental research 2012 Feb;36(2) PMID: 22085135 PMCID: PMC3268944.
  16. Buchowski Maciej S, Meade Natalie N, Charboneau Evonne, Park Sohee, Dietrich Mary S, Cowan Ronald L, Martin Peter R. Aerobic exercise training reduces cannabis craving and use in non-treatment seeking cannabis-dependent adults. PloS one 2011 Mar;6(3) PMID: 21408154 PMCID: PMC3050879.
  17. Reich Michael S, Dietrich Mary S, Martin Peter R. Temporal sequence of incident cigarette, coffee, and alcohol use among AA participants. The American journal of drug and alcohol abuse 2011 Jan;37(1) PMID: 21128877.
  18. Waddell Kevin W, Zanjanipour Parham, Pradhan Subechhya, Xu Lei, Welch Edward B, Joers James M, Martin Peter R, Avison Malcolm J, Gore John C. Anterior cingulate and cerebellar GABA and Glu correlations measured by ¹H J-difference spectroscopy. Magnetic resonance imaging 2011 Jan;29(1) PMID: 20884148 PMCID: PMC3005886.
  19. Benningfield Margaret M, Arria Amelia M, Kaltenbach Karol, Heil Sarah H, Stine Susan M, Coyle Mara G, Fischer Gabriele, Jones Hendrée E, Martin Peter R. Co-occurring psychiatric symptoms are associated with increased psychological, social, and medical impairment in opioid dependent pregnant women. The American journal on addictions 2010 Sep;19(5) PMID: 20716304 PMCID: PMC2924760.
  20. Parks Mitchell H, Greenberg Daniel S, Nickel Mark K, Dietrich Mary S, Rogers Baxter P, Martin Peter R. Recruitment of additional brain regions to accomplish simple motor tasks in chronic alcohol-dependent patients. Alcoholism, clinical and experimental research 2010 Jun;34(6) PMID: 20374203.
  21. Martin Peter R, Arria Amelia M, Fischer Gabriele, Kaltenbach Karol, Heil Sarah H, Stine Susan M, Coyle Mara G, Selby Peter, Jones Hendrée E. Psychopharmacologic management of opioid-dependent women during pregnancy. The American journal on addictions 2009 Mar;18(2) PMID: 19283567 PMCID: PMC2777700.
  22. Reich Michael S, Dietrich Mary S, Finlayson Alistair James Reid, Fischer Edward F, Martin Peter R. Coffee and cigarette consumption and perceived effects in recovering alcoholics participating in Alcoholics Anonymous in Nashville, Tennessee, USA. Alcoholism, clinical and experimental research 2008 Oct;32(10) PMID: 18657129 PMCID: PMC2585746.
  23. Raj Vidya, Landess Jacqueline S, Martin Peter R. Oxcarbazepine use in essential tremor. The Annals of pharmacotherapy 2006 Oct;40(10) PMID: 16968828.
  24. Farah Adriana, de Paulis Tomas, Moreira Daniel P, Trugo Luiz C, Martin Peter R. Chlorogenic acids and lactones in regular and water-decaffeinated arabica coffees. Journal of agricultural and food chemistry 2006 Jan;54(2) PMID: 16417293.
  25. Farah Adriana, de Paulis Tomas, Trugo Luiz C, Martin Peter R. Effect of roasting on the formation of chlorogenic acid lactones in coffee. Journal of agricultural and food chemistry 2005 Mar;53(5) PMID: 15740032.
  26. Martin Peter R, Petry Nancy M. Are non-substance-related addictions really addictions?. The American journal on addictions 2005 Jan;14(1) PMID: 15804872.
  27. Shearer Jane, Fueger Patrick T, Rottman Jeffrey N, Bracy Deanna P, Martin Paul H, Wasserman David H. AMPK stimulation increases LCFA but not glucose clearance in cardiac muscle in vivo. American journal of physiology. Endocrinology and metabolism 2004 Nov;287(5) PMID: 15265760.
  28. de Paulis Tomas, Commers Patricia, Farah Adriana, Zhao Jiali, McDonald Michael P, Galici Ruggero, Martin Peter R. 4-Caffeoyl-1,5-quinide in roasted coffee inhibits [3H]naloxone binding and reverses anti-nociceptive effects of morphine in mice. Psychopharmacology 2004 Nov;176(2) PMID: 15088081.
  29. Parks Mitchell H, Morgan Victoria L, Pickens David R, Price Ronald R, Dietrich Mary S, Nickel Mark K, Martin Peter R. Brain fMRI activation associated with self-paced finger tapping in chronic alcohol-dependent patients. Alcoholism, clinical and experimental research 2003 Apr;27(4) PMID: 12711934.
  30. Martin Peter R, Singleton Charles K, Hiller-Sturmhöfel Susanne. The role of thiamine deficiency in alcoholic brain disease. Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism 2003; 27(2) PMID: 15303623.

PubMed Listing of Vanderbilt Publications