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Cody Heiser

University of Texas

Ken Lau lab

Tumors arising from the colonic epithelium follow complex progression patterns involving admixtures of cell types across a spectrum of differential states. Tumor composition and microenvironmental interactions throughout the adenoma-to-carcinoma sequence have not been adequately characterized at the single-cell level. By applying novel machine learning and spatial modeling techniques to scRNA-seq and multiplex immunofluorescence data from human tumor specimens, I hope to build an integrated, systems-level understanding of CRC disease progression.