University of Georgia
Breann Brown lab
Heme biosynthesis is an essential pathway in most organisms, allowing for processes such as cellular respiration and photosynthesis. Our lab uses biophysical techniques such as X-ray crystallography to study the enzymes that are part of the eight steps within the pathway. My research focuses on the housekeeping isoform of 5-aminolevulinic acid synthase (ALAS1), which catalyzes the first and rate-limiting step.