{"id":3834,"date":"2024-03-27T20:01:40","date_gmt":"2024-03-27T20:01:40","guid":{"rendered":"https:\/\/medschool.prd.vanderbilt.edu\/vanderbilt-medicine\/?p=3834"},"modified":"2024-03-27T20:01:40","modified_gmt":"2024-03-27T20:01:40","slug":"a-vanderbilt-first","status":"publish","type":"post","link":"https:\/\/medschool.vanderbilt.edu\/vanderbilt-medicine\/a-vanderbilt-first\/","title":{"rendered":"A Vanderbilt first"},"content":{"rendered":"
\"\"
Transplant patient Connie Rankin was cleared to return home to Memphis just in time for the holidays. Photo by Erin O. Smith.<\/figcaption><\/figure>\n

Vanderbilt University Medical Center recently performed its first combined lung and liver transplant. Connie Rankin of Memphis, Tennessee, received the transplant, which involved dozens of specialists, including transplant teams for both organs. Her lung transplant was performed by Matthew Bacchetta, MD, MBA, professor of Cardiac Surgery and Biomedical Engineering; and her liver transplant was performed by Seth Karp, MD, H. William Scott Jr. Professor and chair of the Section of Surgical Sciences.<\/p>\n

Rankin was diagnosed in 2001 with sarcoidosis, a rare autoimmune disease that causes excess tissue to develop in organs of the body. It affected both her liver and lungs. Her lung function got worse over the years, but she was able to live with it until 2022, when she contracted COVID-19, and her breathing became much worse. Doctors estimated she had two years to live if she didn\u2019t get a transplant. \u201cShe was at end stage when we met her for the first time,\u201d said Bacchetta, the H. William Scott Jr. Professor of Surgery.<\/p>\n

Her liver was also failing, and her eyes were yellow with jaundice.<\/p>\n

Rankin had a big decision \u2014 whether to become the first person to undergo a lung-liver transplant at Vanderbilt. She knew the risks but talked at length about the possible benefits with Eric Lambright, MD, associate professor and surgical director of the Lung Transplant Program. \u201cIt occurred to me\u2026there is the possibility that the surgery could be successful, and then I could once again breathe in \u2018room air\u2019 like normal people,\u201d Rankin said.<\/p>\n

VUMC placed her on the transplant list in May 2023, and she began waiting for the gift of lungs and a liver from a deceased organ donor. The wait could have been months, because the donor would have to match her size and blood type and other factors.<\/p>\n

Having been on the waiting list only 24 hours, Rankin\u2019s phone rang. Her matching organs were available. She knew she needed to depart for Nashville, but she was awestruck.<\/p>\n

\u201cI sat there an hour, and I had to get my mind right,\u201d she said. \u201cI was praying, and I was like \u2018OK, well, Lord, you know, you brought me to it. So, I\u2019m going to trust you to bring me through it.\u2019 And from that point on, all the fear left me. I knew that I was at one of the top hospitals in the country with some of the best doctors.\u201d<\/p>\n

On the day of the complex surgery, surgeons first removed one of her lungs and placed her on ECMO (extracorporeal membrane oxygenation), a life-sustaining mechanical system that temporarily takes over for the heart and lungs of critically ill patients. Then the liver team completed her liver transplant, while her donor lungs were preserved in a new, special laboratory-grade refrigerator. Bacchetta said the refrigerator allows organs to be preserved for up to 20 hours, a major increase from the typical eight hours, allowing for longer and more complex multi-organ transplants.<\/p>\n

After the liver transplant was complete, the lung team completed its transplant.<\/p>\n

\u201cThere aren\u2019t many institutions that could do that well and provide this type of outcome for her,\u201d Bacchetta said.<\/p>\n

\u201cThis case really shows the Vanderbilt Transplant Center\u2019s commitment to our patients, using a multidisciplinary approach to offer personalized care and achieve the best outcomes,\u201d said Martin Montenovo, MD, MMHC, chief of the Division of Hepatobiliary Surgery and Liver Transplantation in the Department of Surgery. \u201cWe have the resources; we have the expertise; and we have the innovation to make complex transplants successful.\u201d<\/p>\n

In all, due to complications, Rankin would have five different surgeries over one weekend. Her kidneys shut down, and she had to go on dialysis. She had an unexpected tracheotomy due to a need for oxygen.<\/p>\n

Two weeks later, when the tracheotomy tube was removed, she initially didn\u2019t realize she was breathing \u201croom air,\u201d not medical oxygen.<\/p>\n

\u201cI felt like I was born again or something,\u201d she said. \u201cIt was just amazing to me \u2026 not being attached to the oxygen. I could move freely about. Even now I\u2019m just still amazed.\u201d<\/p>\n

During her stay at Stallworth Rehabilitation Hospital, her kidney function returned, and she no longer needed dialysis.<\/p>\n

After leaving the hospital, Rankin recovered at an apartment in Nashville. The week before Thanksgiving, she was cleared to return home to Memphis, just in time for the holidays.<\/p>\n

\u201cThere are more milestones to accomplish, and my healing continues, but life is so much better already,\u201d Rankin said.<\/p>\n

\u201cI had an awesome team \u2014 the nurses, the doctors, the therapists and my caregivers,\u201d she said. \u201cI\u2019m just so grateful.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"

Vanderbilt University Medical Center recently performed its first combined lung and liver transplant. Connie Rankin of Memphis, Tennessee, received the transplant, which involved dozens of specialists, including transplant teams for both organs. Her lung transplant was performed by Matthew Bacchetta, MD, MBA, professor of Cardiac Surgery and Biomedical Engineering; and her liver transplant was performed…<\/p>\n","protected":false},"author":222,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"_links_to":"","_links_to_target":""},"categories":[11,47],"tags":[],"class_list":["post-3834","post","type-post","status-publish","format-standard","hentry","category-vm-around-the-medical-center","category-vm-spring-2024"],"acf":[],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/pcDnub-ZQ","_links":{"self":[{"href":"https:\/\/medschool.vanderbilt.edu\/vanderbilt-medicine\/wp-json\/wp\/v2\/posts\/3834","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medschool.vanderbilt.edu\/vanderbilt-medicine\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medschool.vanderbilt.edu\/vanderbilt-medicine\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medschool.vanderbilt.edu\/vanderbilt-medicine\/wp-json\/wp\/v2\/users\/222"}],"replies":[{"embeddable":true,"href":"https:\/\/medschool.vanderbilt.edu\/vanderbilt-medicine\/wp-json\/wp\/v2\/comments?post=3834"}],"version-history":[{"count":2,"href":"https:\/\/medschool.vanderbilt.edu\/vanderbilt-medicine\/wp-json\/wp\/v2\/posts\/3834\/revisions"}],"predecessor-version":[{"id":3970,"href":"https:\/\/medschool.vanderbilt.edu\/vanderbilt-medicine\/wp-json\/wp\/v2\/posts\/3834\/revisions\/3970"}],"wp:attachment":[{"href":"https:\/\/medschool.vanderbilt.edu\/vanderbilt-medicine\/wp-json\/wp\/v2\/media?parent=3834"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medschool.vanderbilt.edu\/vanderbilt-medicine\/wp-json\/wp\/v2\/categories?post=3834"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medschool.vanderbilt.edu\/vanderbilt-medicine\/wp-json\/wp\/v2\/tags?post=3834"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}