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Heidi Hamm, Ph.D.

Professor - Aileen M. Lange and Annie Mary Lyle Chair, Departments of Pharmacology, Cardiovascular Research, Ophthalmology and Visual Sciences, and Orthopedic Surgery and Rehabilitation


Areas of Interest: Neuroscience; Cell Signaling; Natural Products

Member: VICC

Dr. Hamm’s work is focused on understanding the molecular basis of signaling mechanisms mediated by G proteins, which are switch proteins. G proteins are normally inactive, but a receptor that has received a specific signal can activate G proteins, leading to changes in the activity of enzymes that produce second messengers such as cyclic AMP and calcium.

The resulting changes in cellular activity underlie a large number of physiological processes. G protein-mediated signalling cascades are key regulators of many physiological processes, including processes of development, differentiation, and regulation of cell division.


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