- Noble KN, Wente SR. Nuclear mRNA on the move. Nature cell biology. 2010 Jun;12(6). 525-7. PMID: 20517300 [PubMed].
Innovations in live-cell microscopy and single-molecule analysis have allowed a new direct view of nuclear messenger RNA dynamics. A new study extends previous analyses of mRNA-protein intranuclear transport and links this critical step to the kinetics of moving through nuclear pore complexes. Seeing nuclear mRNA on the move will impact future work on pore translocation and nuclear organization.