My research is directed at determining the epigenetic mechanisms that interact with the intrinsic transcriptional programs and govern the formation and behavior of various progenitor populations in the developing pancreas. The knowledge obtained will have direct implications with respect to how specific cell populations induce and undergo critical progenitor cell fate decisions, such as tip-trunk lineage allocation. There will also be a direct translational relevance, because we will learn how to enhance progenitor cell specification, and ultimately β-cell formation, from human embryonic stem cells for cellular diabetes therapy.
Postdoctoral Fellow, Cell & Developmental Biology
VUMC/Stem Cell & Developmental Biology 9465 MRB IVNashville 37232-0494
(615) 343-8258 (lab)