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Directed migration: Cells navigate by extracellular vesicles.


AUTHORS

Sung BH , Weaver AM , . The Journal of cell biology. 2018 8 6; ().

ABSTRACT

Directional cell motility toward a chemical gradient, chemotaxis, is critical during inflammation, embryogenesis, and cancer metastasis. In this issue, Kriebel et al. (2018. https://doi.org/10.1083/jcb.201710170) demonstrate that the key cAMP chemoattractant for amoebas is synthesized within and released from extracellular vesicles to promote chemotaxis.



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