The Department of Cell and Developmental Biology began as Anatomy in 1925, evolved to Cell Biology and was reorganized in 2001/2002 to reflect unification of cellular and developmental biology disciplines in one department. This has offered unique opportunities for reciprocal and collaborative interactions on cutting edge biomedical research. The field of cell biology has traditionally focused on questions regarding subcellular machinery and the regulated communication of extracellular or growth signals and cues. An ultimate application of the knowledge gleaned from such studies of single cells has been to understand functions in multi-cellular organisms and human biology/medicine. This directly links to the problems of interest to developmental biologists, including the mechanisms for morphogenesis, tissue polarity and patterning. By building bridges between researchers working in cell and/or developmental biology fields the department has developed an interactive and exciting environment.