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Working with Billy Hudson's lab in the department of medicine, the Page-McCaw lab determined that the element bromine is required for crosslinking basement membrane, the extracellular matrix underlying all epithelial tissues.  Without bromine, the basement membrane is weakened and fruitflies cannot survive.  As this basement-membrane crosslink is highly conserved throughout… Read More

The Par3-like polarity protein Par3L is essential for mammary stem cell maintenance.a Yongliang Huo & Ian G. Macara Nature Cell Biology 16, 529–537 (2014) doi:10.1038/ncb2969 Received 01 August 2013, Accepted 11 April 2014, Published online 25 May 2014, Corrected online 30 May 2014 Abstract The Par polarity… Read More

Motor and Tail Homology 1 (TH1) Domains Antagonistically Control Myosin-1 Dynamics Jessica N. Mazerik, Lewis J. Kraft, Anne K. Kenworthy, Matthew J. Tyska Abstract Class 1 myosins are monomeric motor proteins that fulfill diverse functions at the membrane/cytoskeletal interface. All myosins-1 contain a motor domain, which binds… Read More