Acknowledgment Reminder: If your research utilized VICB core facilities, please remember to acknowledge the appropriate core facility in all resulting publications. Proper acknowledgment helps demonstrate the impact of our shared resources and supports continued access to these capabilities.
Latest Publications
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Supermeres containing Discoidin Domain Receptor 1 extracellular domain promote collagen alignment and immune exclusion in microsatellite stable colorectal cancer. Cancer Research Communications.
Maxwell Stuart Hamilton*, Samuel Ellis, Zheng Cao, Oleg Tutanov, Alan Simmons, Radhika Aramandla, James Higginbotham, Marisol Ramirez, Katherine Schnee, Matthew Bechard, Harsimran Kaur, Jeffrey Franklin, Swastika Mandal, Ken Lau, Qi Liu, Jeremy Goettel, Ambra Pozzi, Robert Coffey*.Supported by the Cell Imaging Shared Resource.
Substrate-Dependent Crosslinking by the Cytochrome P450 From Aminopyruvatide Biosynthesis. Angewandte Chemie International Edition.
Chandrashekhar Padhi* (University of Illinois at Urbana-Champaign), Douglas Mitchell.De Novo Design in an M1 Positive Allosteric Modulator Backup Program: The Discovery of VU6069863. ACS Medicinal Chemistry Letters.
Changho Han*, Upendra Rathnayake, Alison Gregro, Julie Engers, Christopher Presley, Nathan Schley, Analisa Thompson Gray, Michael Bubser, Hyekyung Cho, Alice Rodriguez, Valerie Kramlinger, Olivier Boutaud, Colleen Niswender, Carrie Jones, Darren Engers, Craig Lindsley*.Cryo-electron tomography of functionally validated synapses in human induced neurons. Structure.
Houcek AJ, Sun R, Rothfuss SJ, Chalkley OR, Kavalali ET, Zhou Q.Phosphoinositides and inositol phosphates as molecular glues. FEBS Lett.
Seaton-Terry A, Cutright AJ, Loi MNC, Martin J, Gilligan JW, Kubina JN, Arambula MJ, Palmu ST, Zhou D, Blind RD.Heme as a Versatile Signaling Molecule: Coordinating Mitochondrial Metabolism with Global Cellular Responses. Journal of Biological Chemistry.
Iva Chitrakar*, Breann Brown*.Characterization of Regioisomeric Conjugates Arising from Pixantrone at AP Sites in DNA. Biochemistry.
Yizhi Fu*, John Terrell, Andrew Kellum, Pradeep Pallan, Carmelo Rizzo, Martin Egli, Michael Stone*.
Human Milk Oligosaccharides Modulate Nitrogen Utilization in Lactobacillus crispatus in a Glucose-Dependent Manner. ACS Infect Dis.
Talbert JA, Kalmer TL, Walker AS, Gaddy JA, Townsend SD.
MutexaGPT: an intuition-to-design translator for physics-based enzyme engineering. Nat Comput Sci
Shao Q, Zhong Y, Stull S, Ran X, Ding N, Nehil-Puleo K, Yao R, Xu H, Yang ZJ.Kv11.1 (hERG) Protein Interaction Networks Connect Endocytic Trafficking to Polygenic Influences on Cardiac Repolarization. Mol Cell Proteomics.
Egly CL, Barny LA, Woo S, Mitchell D, Ku M, Knollmann BC, Plate L, Kroncke BM.Clostridioides difficile couples responses to host nutritional immunity and a commensal-derived antibiotic to enable growth in the gut. Sci Signal.
Douglass MV, Melton LR, Calcutt MW, McNeely TP, Price SL, Munneke MJ, Skaar EP.
SpxA1 and SpxA2 function as a stoichiometry-dependent regulatory rheostat governing virulence gene expression in group A Streptococcus. mBio.
Morrison GA, Vega LA, Sanson Iglesias M, Holly K Jr, McDonald WH, Horstmann N, Shelburne SA, Gaddy JA, Flores AR.Opposing effects of Lrig1 and Lrig3 on EGFR maintain intestinal homeostasis and mitigate likelihood of colonic neoplasia. Cellular and Molecular Gastroenterology and Hepatology.
Matthew Bechard, Zhengyi Chen, Ping Zhao, Radhika Aramandla, Yilin Yang, Alan Simmons, M. Kay Washington, Jeffery Franklin, Ken Lau, Robert Coffey.
Supported by the Cell Imaging Shared Resource and the Vanderbilt Genome Editing Resource.Morning glucagon disrupts insulin induced hepatic metabolic memory and subsequent afternoon glucose metabolism in canines. Frontiers in Endocrinology.
Hannah Waterman*, Marta Smith, Ben Farmer, Kalisha Yankey, Karin Bosma, Richard O'Brien, Derek Claxton, Tristan Howard, Guillaume Kraft, Alan Cherrington, Dale Edgerton.