Acknowledgment Reminder: If your research utilized VICB core facilities, please remember to acknowledge the appropriate core facility in all resulting publications. Proper acknowledgment helps demonstrate the impact of our shared resources and supports continued access to these capabilities.
Latest Publications
-
WNK463 stimulates K-Cl cotransport independently of WNK kinase activity. Am J Physiol Cell Physiol.
Ferdaus MZ, Terker AS, Li L, Days EL, Bauer JA, Delpire E.Drug repurposing identifies candidate uterus-selective tocolytics for preterm labor. Science Translational Medicine.
Shajila Siricilla*, Christopher Hansen, Jeremy Staub, Jordan Walker, Alexus Brown, Sydney Cole, Debasmita De, Lauren Hatcher, Carolyn Simpson, Jackson Rogers, Naoko Boatwright, Stacey Crockett, Deanna Sekulich, Christian Meyer, Vito Quaranta, Quanhu Sheng, John Benjamin, J. M. Newton, Bibhash Paria, Jeff Reese, Jennifer Herington*.
Supported by the High-Throughput Screening Facility.
Review of the selectivity of chlorzoxazone 6-hydroxylation as a probe for human cytochrome P450 2E1. Drug Metab Dispos.
Guengerich FP, Yamazaki H.
Human milk oligosaccharides are distinctly processed by early life gut microbial sialidases. Gut Microbes.
Plisko OL, Chapel VS, Sekela JJ, Talbert JA, Townsend SD, Zemel BS, Wu GD, R Redinbo M.Substrate Length Controls Atropopeptide Complexity and Triggers Excision-Driven Scaffold Hop to Diketopiperazine Alkaloids. J Am Chem Soc.
Tan B, Cui Z, Kakumu Y, Panczyk SJ, Ikeda M, Liu D, Pestalozzi CM, Vorholt JA, Walker AS, Hardes K, Grininger M, Helfrich EJN.
PBPK Modeling Investigation of IVIVE-Observed Pharmacokinetic Divergence for VU0467319: A Mechanistic Refinement Workflow for Low-Solubility Compounds. Pharmaceutics.
Abisogun AA, Krishnan S, Lindsley CW, Boutaud O.Combined muscarinic receptor M1 and M4 stimulation reverses cocaine-induced attention deficits in male mice. Journal of Psychopharmacology.
Lærke Bornø* (Copenhagen University Hospital—Bispebjerg and Frederiksberg), Craig Lindsley.
TMEM175: Lysosomal Ion Channel Physiology, Therapeutic Potential, and Emerging Pharmacology. Am J Physiol Cell Physiol.
Li K, Le SD, Denton JS.The Central Coupler of ClpXP Controls Intersubunit Communication and Couples Intrasubunit Chemical Energy with Force Generation. bioRxiv [Preprint].
Sosa RP, Florez Ariza AJ, Kim J, Tong A, Kang ZH, Li A, Kuriyan J, Bustamante C.A Gata4-Loxl2 axis controls ECM remodeling to enable scar-free spinal cord regeneration in zebrafish. Cell Rep.
Noel NP, Lima Fernandes VF, Kjar A, Pfotenhauer PE, Kim H, Sefogbe MP, Akam-Baxter EA, Lippmann ES, Cigliola V.Nitro-arachidonic acid inhibits prostaglandin endoperoxide H synthase 2 through histidine-mediated heme-binding conformational perturbation. Arch Biochem Biophys.
Wood I, Grosso F, Bonilla L, Radi R, Goodman M, Marnett LJ, Trostchansky A, Rubbo H.
Substrate-Dependent Crosslinking by the Cytochrome P450 From Aminopyruvatide Biosynthesis. Angew Chem Int Ed Engl.
Padhi C, Nguyen DT, Zhu L, Cha L, Wald JW, Mitchell DA, van der Donk WA.
Kv11.1 (hERG) Protein Interaction Networks Connect Endocytic Trafficking to Polygenic Influences on Cardiac Repolarization. Mol Cell Proteomics.
Egly CL, Barny LA, Woo S, Mitchell D, Ku M, Knollmann BC, Plate L, Kroncke BM.
Heme as a versatile signaling molecule: Coordinating mitochondrial metabolism with global cellular responses. J Biol Chem.
Chitrakar I, Brown BL.Biosynthesis and analytics of specialized pro-resolving mediators: facts and faults. J Lipid Res.
Schebb NH, Kühn H, Kampschulte N, Flamand N, Peters-Golden M, Jakobsson PJ, Claesson HE, Weylandt KH, Rohwer N, Saul MJ, Proschak E, Brüne B, Garscha U, Maier TJ, Patrignani P, Gijón MA, Schopfer FJ, Gelhaus SL, Gelb MH, Murphy RC, Skarke C, Brash AR, Freeman BA, Blair IA, Gilroy DW, Geisslinger G, Hanson J, Ekroos K, FitzGerald GA, Kahnt AS, O'Donnell VB, Alnouri MW, Offermanns S, Steinhilber D.Introduction: Insertion and Folding of Membrane Proteins and Peptides. Chemical Reviews.
Paula Booth* (King’s College London), Charles Sanders*.Protein Thioether Crosslinks Installed by a SPASM-Containing Radical SAM Enzyme from Methanogenic Archaea. ACS Bio & Med Chem Au.
Emily Dieter* (Montana State University), Austin Woodard, Douglas Mitchell.Supported by the Mass Spectrometry Research Center.
Comparative analysis of KMT2A fusions in human models of acute myeloid leukemia. Experimental Hematology.
Safia Safa-Tahar-Henni* (Institute for Research in Immunology and Cancer), Walter Chazin.The iron-binding siderophore enterobactin is required for the response of multi-drug resistant Klebsiella pneumoniae to zinc limitation (preprint). bioRxiv.
Jeffrey Singer*, D. Annie Doyle, Dillon Kunkle, Owen Burroughs, Rachel Service, Walter Chazin, Eric Skaar*.Supported by the Mass Spectrometry Research Center.