Latest Publications
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- Expression and purification of Steroidogenic Factor-1 (NR5A1) nuclear receptor ligand binding domain complexed with the signaling phosphoinositide lipid PI(3,4,5)P (chapter). Methods in Enzymology, Volume 728: Lipids and Membranes: Metabolism, Lipidation, and Lipid-Protein Interactions.
Alexis Campbell*, Alexander Cutright, Jessica Martin, Arwa Kheda, Mong Na Claire Loi. Raymond Blind* - Regulation of Cholesterol and Triglyceride Metabolism by Fatty acid Ethanolamides. Current Atherosclerosis Reports.
Sean Davies*, Reza Fadaei. - An anaerobic pathogen rewires host metabolism to fuel oxidative growth in the inflamed gut. Cell.
Luisella Spiga*, Ryan Fansler*, Yifan Wu*, Alexandra Grote* (Broad Institute of MIT and Harvard), Madison Langford-Butler, Asia Miller, Owen Hale, Deepanshu Singla, M Wade Calcutt, Abigail Rose, Madeline Bresson, Alexandra Schrimpe-Rutledge, Simona Codreanu, Mary Kay Washington, Benjamin Bratton, Stacy Sherrod, John McLean, Megan Behringer, Lili Tao, Danyvid Olivares-Villagómez, Wenhan Zhu*.
Supported by the Mass Spectrometry Research Center. - Human Brain Vasculature-on-a-Chip Model Constructed With Microvessels Isolated From Cryopreserved Postmortem Human Brain Tissue. Advanced Healthcare Materials.
Brian O'Grady, A. Scott McCall, Samuel Cullison, Daniel Chavarria, Matthew Schrag, Ethan Lippmann*.
Supported by the Cell Imaging Shared Resource. - Shaping of the Infant Gut Microbiome by Milk Oligosaccharides. Annual Review of Biochemistry.
Victoria Federico*, David Cliffel, Jennifer Gaddy, Steven Townsend*. - Automated cGMP optical labeling of FDA-approved antibodies for human use. Nature Protocols.
Kamal Jouad*, Marisa Hom, Ashtyn McAdoo, J. Oliver McIntyre, Eben Rosenthal, Adam Rosenberg* - Islet cell DNA methylation in human ageing and diabetes. Nature Metabolism.
Emily Hodges*, Guoqiang Gu*. - The intestinal microbiota impacts nutritional immunity and resistance to Acinetobacter baumannii pneumonia. eLife.
Erin Green* (University of Chicago), Nicholas Negretti, Nicolas Shealy, Felipe Moser, Sydney Drury, Kacie Traina, Valeria Reyes Ruiz, Tzushan Yang, Mariana Byndloss, Raf van de Plas, Jennifer Sucre, Eric Skaar*. - Towards a unified molecular mechanism for ligand-dependent activation of NR4A-RXR heterodimers. eLife.
Xiaoyu Yu*, Douglas Kojetin*. - Actomyosin contractility is a potent suppressor of mesoderm induction by human pluripotent stem cells. Journal of Cell Biology.
Loic Fort*, Vaishna Vamadevan, Wenjun Wang, Ian Macara*. - Phenoxy-Benzothiadiazole Donor-Acceptor Compounds Exhibit Solvatochromic Fluorescence and Are Precursors to Open-Shell Phenoxyl Radicals. J Org Chem. Stanley AM, Tremblay C, Schley ND, Buckley HL, Leitch DC, Chernick ET.
- Structure-guided optimization of SLC1A1/EAAT3-selective inhibitors targeting renal cancer metabolism. EMBO J. Koochaki P, Qiu B, Coker JA, Earsley A, Wang NS, Romigh T, Goins CM, Salem C, Mi D, Days E, Bauer JA, Stauffer SR, Boudker O, Chakraborty AA.
- Unmasking pathogen traits for chronic colonization in neurogenic bladder. Cell Rep. Reasoner SA, Frainey BT, Hale OF, Borden A, Graham MK, Turner E, Brenes LR, Soderstrom CBW, Green H, Schmitz JE, Laub MT, Kelly MS, Clayton DB, Hadjifrangiskou M.
- AI-Assisted Isolation of Bioactive Dipyrimicins from Amycolatopsis azurea and Identification of Their Corresponding Dip Biosynthetic Gene Cluster. J Nat Prod. Ancajas CMF, Shuster I, Walker AS.
- Integrated Genomic and Transcriptomic Study Reveals MAPK11 and PER1 as Important Obesity Susceptibility Genes in a High-Risk Hispanic/Latino Population. Circ Genom Precis Med. Kim D, Polikowsky HG, Highland HM, Chen HH, Zhu W, Zhang X, Gillman MG, Frankel EG, Roshani R, Landman JM, Wang Y, Young KL, Anwar MY, Krishnan M, Buchanan VL, Berndt SI, Arias JD, Raffield LM, Gutierrez AD, Bishehsari F, Lee M, McCormick JB, Fisher-Hoch SP, Below JE, North KE, Graff M.
- Overcoming the Barrier to Intermolecular Alkoxy Radical Reactivity: Proton-Coupled Electron Transfer-Mediated Alkene Hydroetherification. J Am Chem Soc. Delgutte LC, Hua Y, Lee J, Lugo AN, Iyengar AR, Kim DE.
- Expression and purification of Steroidogenic Factor-1 (NR5A1) nuclear receptor ligand binding domain complexed with the signaling phosphoinositide lipid PI(3,4,5)P (chapter). Methods in Enzymology, Volume 728: Lipids and Membranes: Metabolism, Lipidation, and Lipid-Protein Interactions.