Publications

Latest Publications

• Stable and Tunable Expression of Human Peripheral Myelin Protein 22 in Rat Schwann Cells. Journal of Biological Chemistry.
  Mason Wilkinson*, Katherine Stefanski*, Pramod Gowda*, Bruce Carter, Charles Sanders*.

  Protein-enhanced small molecule disruptors of ordered membrane domains. Proceedings of the National Academy of Sciences.
  Katherine Stefanski*, Geoffrey Li, Nilabh Saksena, Yelyzaveta Zuy, Alexander Fisch, Thomas Hasaka, Joshua Bauer, Charles Sanders*.

  Supported by the Cell Imaging Shared Resource and the High-Throughput Screening Facility.

  Targeting glucagon signaling in metabolic disorders, functional insights from zebrafish receptor knockouts. Cellular and Molecular Life Sciences.
  Ashraf Al Madhoun* (Dasman Diabetes Institute), Wenbiao Chen.

  Profiling the CFTR Variant Selectivity and Off-Target Interactions of VX-121 (preprint). bioRxiv.
  Ashish Jhangiani* (Purdue University), John Olson III*, Mia Perfetti, Grace Abell, Crissey Cameron, Liudmyla Arifova, Kaitlyn Ledwitch, Jens Meiler, Lars Plate*.

  Supported by the Molecular Design and Synthesis Center.

  Discovery of VU6066098: A Selective and CNS-Penetrant mGlu₂ NAM with Robust Antidepressant-, Antipsychotic-, and Procognitive-like Activity in Rodents. ACS Chemical Neuroscience.
  Jeremy Coleman*, Rory Capstick, Sichen Chang, Derek Rios, Michael Bubser, Analisa Thompson Gray, Irene Zagol-Ikapitte, Srinivasan Krishnan, Hyekyung Cho, Alice Rodriguez, Colleen Niswender, Olivier Boutaud, Darren Engers, Carrie Jones*, Craig Lindsley*.

  Protein-enhanced small molecule disruptors of ordered membrane domains. Proc Natl Acad Sci U S A.

  Stefanski KM, Li GC, Luu DD, Fosu KK, Guadarrama E, Hutchison JM, Saksena N, Zuy Y, Fisch AJ, Hasaka TP, Bauer JA, George AL Jr, Kenworthy AK, Horn WDV, Sanders CR.

  SLC11A2 withholds divalent metals from Salmonella in the gut epithelium. Proc Natl Acad Sci U S A.
  Norberg ES, Westerman TL, Cruz E, Bushman SD, Salogiannis J, Skaar EP, Elfenbein JR, Knodler LA.

  
  Shaping of the Infant Gut Microbiome by Milk Oligosaccharides. Annu Rev Biochem.
  Federico VA, Cliffel DE, Gaddy JA, Townsend SD.

  
  Interactomics of SARS-CoV-2 Macrodomain 1 Reveals Putative Clients of ADP-Ribosyl Hydrolase Activity. Viruses.
  Cameron CD, Heilmann G, Roman BK, Plate L.

  
  An anaerobic pathogen rewires host metabolism to fuel oxidative growth in the inflamed gut. Cell.
  Spiga L, Fansler RT, Wu Y, Grote A, Langford-Butler M, Miller AK, Neal M, Hale OF, Singla D, Calcutt MW, Rose AE, Bresson MM, Schrimpe-Rutledge AC, Berdy B, Codreanu SG, Washington MK, Bratton BP, Sherrod SD, McLean JA, Zengler K, Sears CL, Behringer MG, Gnirke A, Tao L, Livny J, Olivares-Villagómez D, Earl AM, Zhu W.

  Single-cell RNA sequencing reveals disease associated changes in brain endothelial cells in the 5XFAD mouse. Fluids Barriers CNS.
  Embalabala RJ, Masters H, Ziehm E, Pouncey J, Kim H, Lippmann ES.