Publications

Latest Publications

• • Structure-based discovery and definition of RiPP recognition elements. mSystems.
    Miriam Bregman* (University of Illinois at Urbana-Champaign), Andrew Rice, Shravan Dommaraju, Douglas Mitchell*.
  • A periplasmic zinc capture protein enhances the resistance of Neisseria gonorrhoeae to nutritional immunity. Proceedings of the National Academy of Sciences.
    Ian Liyayi* (University of Virginia), Yasiru Perera, Indu Bhatia, Walter Chazin.
  • Pharmacological Tools to Modulate Ordered Membrane Domains and Order-Dependent Protein Function (preprint). bioRxiv.
    Katherine Stefanski*, Hui Huang, Nilabh Saksena, Alexander Fisch, Thomas Hasaka, Joshua Bauer, Charles Sanders*.
    Supported by the High-Throughput Screening Facility.
  • Fragment-to-Lead Medicinal Chemistry Publications in 2024: A Tenth Annual Perspective. Journal of Medicinal Chemistry.
    David Twigg* (Astex Pharmaceuticals), Stephen Fesik.
  • CLASP1/2 regulate immune synapse maturation in natural killer cells. Journal of Leukocyte Biology.
    Alejandro Pariani* (Universidad Nacional de Rosario), James Goldenring, Irina Kaverina.
  • Drug-bound outward-facing conformation of a heterodimeric ABC exporter suggests a putative mechanism of drug translocation. Nature Communications.
    Qingyu Tang*, Paola Bisignano, Hassane Mchaourab*.
  • Trypsin Activates Human Platelets via Proteolytic Cleavage of Protease-activated Receptor 4 (PAR4). Thrombosis and Haemostasis.
    Emma Webb*, Kendal Seymour, Heidi Hamm*.
  • Structural Biology Enabling Drug Discovery. Journal of Medicinal Chemistry.
    David Heppner* (University at Buffalo), Craig Lindsley.
  • Chapter Eight: Parameterizing non-canonical amino acids for cyclic peptide simulations (book chapter). Methods in Enzymology, Volume 723: Cyclic Peptides.
    N. Kithmini Wijesiri*, Benjamin Brown*.