Latest Publications
-
- Mechanism of Action of Gepotidacin: Well-Balanced Dual-Targeting against Neisseria gonorrhoeae Gyrase and Topoisomerase IV in Cells and In Vitro. ACS Infectious Diseases.
Alexandria Oviatt*, Jessica Collins, Chelsea Mann, Neil Osheroff*. - Structural Basis of PPARγ-Mediated Transcriptional Repression by the Covalent Inverse Agonist FX-909. Journal of Medicinal Chemistry.
Zane Laughlin*, Liudmyla Arifova, Paola Munoz-Tello, Xiaoyu Yu, Mithun Nag Karadi Giridhar, Jinhui Dong, Joel Harp, Douglas Kojetin*. - FET proteins and PARylation-dependent condensates promote replication fork reversal and genome stability (preprint). bioRxiv.
Celeste Giansanti*, Jack Schultz, David Cortez*. - Large-scale integration of omics and electronic health records to identify potential risk protein biomarkers and therapeutic drugs for cancer prevention. American Journal of Human Genetics.
Qing Li*, Qingyuan Song*, Zhishan Chen*, Jie Ping, Wanqing Wen, Chao Li, Xiao-Ou Shu, Qiuyin Cai, Jirong Long, Bhuminder Singh, Ken Lau, Wei Zheng, Zhijun Yin*, Xingyi Guo*. - Mutant GNAS drives a pyloric metaplasia with tumor suppressive glycans in intraductal papillary mucinous neoplasia. Cell Reports.
Vincent Quoc-Huy Trinh*, Katherine Ankenbauer*, Sabrina Torbit, Christopher Taranto, Jiayue Liu, Frank Revetta, Zhengyi Chen, Angela Kruse, Audra Judd, Celina Copeland, Olivia Ben-Levy, Brenda Jarvis, Monica Brown, Jeffrey Spraggins, Ken Lau, Marcus Tan, Kathleen DelGiorno*.
- Mechanism of Action of Gepotidacin: Well-Balanced Dual-Targeting against Neisseria gonorrhoeae Gyrase and Topoisomerase IV in Cells and In Vitro. ACS Infectious Diseases.