2009/2010 CBMS Journal Club Schedule

Topic	Speaker	Department	Date
Integrin Acts Upstream of Netrin Signaling to Regulate Formation of the Anchor Cell's Invasive Membrane in C. elegans.	David Miller, III, PhD	Cell and Developmental Biology, VUMC	9/1/2009
Phosphorylation of Mcm2 by Cdc7 promotes pre-replication complex assembly during cell-cycle re-entry	Daniel Kaplan, PhD	Biological Sciences, VU	9/8/2009
Polycomb protein Ezh2 regulates pancreatic beta-cell Ink4a/Arf expression and regeneration in diabetes mellitus	Roland Stein, PhD	Molecular Physiology & Biophysics, VUMC	9/15/2009
DCCAMKL-1 and LGR5 Mark Quiescent and Cycling Intestinal Stem Cells Respectively	Jim Goldenring, MD, PhD	Surgery, VUMC	9/22/2009
A mechanism linking extra centrosomes to chromosomal instability	Irina Kaverina, PhD	Cell and Developmental Biology, VUMC	10/6/2009
A developing story: Roles for telomerase beyond the telomere	Kathy Friedman, PhD	Biological Sciences, VU	10/13/2009
Centrosome misorientation reduces stem cell division during ageing	Laura Lee, MD, PhD	Cell and Developmental Biology, VUMC	10/20/2009
Characterization of Cytoplasmic Caspase-2 Activation by Induced Proximity	Sandy Zinkel, MD, PhD	Medicine, VUMC	11/3/2009
Autophagy regulated lipid metabolism	Alyssa M. Hasty, PhD	Molecular Physiology & Biophysics, VUMC	11/17/2009
c-Myc supression of miR-23 enhances mitochondrial glutaminase and glutamine metabolism	Steve Hann, PhD	Cell and Developmental Biology, VUMC	12/1/2009
A mechanism to couple cell length with the cell cycle" based on two papers.	Kathy Gould, PhD	Cell and Developmental Biology, VUMC	12/8/2009
Serum exosomes as mediators of anchorage independent growth	Josiah Ochieng, PhD	Meharry-Vanderbilt Alliance	12/16/2009
Alpha-parvin controls vascular mural cell recruitment to vessel wall by regulating RhoA/ROCK signalling	Roy Zent, MD, PhD	Medicine, VUMC	1/5/2010
Keeping Neurons in Touch. The Fascinating Structure of the AMPA Receptor	Hassane Mchaourab, PhD	Molecular Physiology & Biophysics, VUMC	1/12/2010
MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular synapses in mice	Ron Emeson, PhD	Pharmacology, VUMC	1/26/2010
A Vertebrate gene, ticrr is an essential checkpoint and replication regulator	David Cortez, PhD	Biochemistry, VUMC	2/2/2010
Resistance to Diet-Induced Obesity in Mice with Synthetic Glyoxylate Shunt	John Stafford, MD, PhD	Cell and Developmental Biology, VUMC	2/9/2010
A Structure-based mechanism for vesicle capture by the multisubunit tethering complex Dsi1	Melanie Ohi, PhD	Medicine, VUMC	2/16/2010
G protein subunit Galpha 13 binds to integrin alpha1bbeta3 and meeidates integrin "outside-in" signaling	Ambra Pozzi, PhD	Medicine, VUMC	2/23/2010
Mutations in the Human naked cuticle Homolog NKD1 Found in Colorectal Cancer Alter Wnt/Dvl/beta-catenin Signaling; Myristoylated Naked2 Antagonizes	Bob Coffey, MD	Medicine, VUMC	3/2/2010
The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis and mouse embryonic development	Jason Jessen, PhD	Medicine, VUMC	3/9/2010
MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular synapses in mice	Ron Emeson, PhD	Pharmacology, VUMC	3/16/2010
The Unfolded Protein Response in Health and Disease	Peter Walter	Research Day – Invited Speaker	3/23/2010
EphA2 Mediates Ligand-Dependant Inhibition and Ligand-Independent Promotion of Cell Migration and Invasion via a Reciprocal Regulatory Loop with Akt	Jin Chen, MD, PhD	Medicine, VUMC	3/30/2010
Putting on a Bender: Inducing Membrane Curvature with Small GTP-Binding Proteins	Todd Graham, PhD	Biological Sciences, VU	4/6/2010
Dicer1 functions as a hapionsufficient tumor suppressor	Christine Eischen, PhD	Pathology, VUMC	4/13/2010