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  • Membrane Curvature’s Pore Relation

    Membrane Curvature’s Pore Relation

    ER membrane–bending proteins are necessary for de novo nuclear pore formation T. Renee Dawson1, Michelle D. Lazarus1, Martin W. Hetzer2, and Susan R. Wente1 1 Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, TN 37232 2 Molecular and Cell Biology Laboratory, Salk Institute… Read More

    March 20, 2009

  • Cells cycle with no poles

    Cells cycle with no poles

    Cells cycle with no poles- no poles encodes a predicted E3 ubiquitin ligase required for early embryonic development of Drosophila Julie A. Merkle1, Jamie L. Rickmyre1, Aprajita Garg2, Erin B. Loggins1, Jeanne N. Jodoin1, Ethan Lee1, Louisa P. Wu2 and Laura A. Lee1,* 1 Department of Cell and… Read More

    February 18, 2009

  • Diet and insulin in a stem cell niche Hormonal signaling in the fruit fly

    Diet and insulin in a stem cell niche Hormonal signaling in the fruit fly

    Diet and insulin in a stem cell niche Hormonal signaling in the fruit fly ovary keeps the niche young. Insulin reverses the effects of aging and poor diet, at least on cells within the ovaries of fruit flies. Biologists Daniela Drummond-Barbosa and Hwei-Jan Hsu of Vanderbilt University in… Read More

    January 23, 2009

  • Understanding the molecular mechanisms of stem cell maintenance

    Understanding the molecular mechanisms of stem cell maintenance

    Labosky lab establishes a conserved role for the stem cell gene Foxd3 in maintenance of multipotent neural crest progenitor cells in the mouse embryo. Lu Teng1,*,, Nathan A. Mundell2,4,, Audrey Y. Frist3,4, Qiaohong Wang1 and Patricia A. Labosky1,2,3,4, 1 Department of Cell and Developmental Biology, University of… Read More

    December 30, 2008

  • Vice Chancellor for Research

    Vice Chancellor for Research

    Three Vanderbilt University School of Medicine faculty members are taking on new leadership roles. Susan Wente, Ph.D., has been named assistant vice chancellor for Research. Read More

    November 21, 2008

  • Young Innovator Award

    Young Innovator Award

    NIH Director’s New Innovator Award recipient As part of NIH's commitment to increasing opportunities for new scientists, it has created the NIH Director's New Innovator Award to support exceptionally creative new investigators who propose highly innovative projects that have the potential for unusually high impact. Melanie Ohi recently received the… Read More

    October 6, 2008

  • The Clp1-Cdc14 phosphatase contributes to the robustness of cytokinesis by association with anillin-related Mid1

    The Clp1-Cdc14 phosphatase contributes to the robustness of cytokinesis by association with anillin-related Mid1

    The Clp1/Cdc14 phosphatase contributes to the robustness of cytokinesis by association with anillin-related Mid Cdc14 phosphatases antagonize cyclin-dependent kinase–directed phosphorylation events and are involved in several facets of cell cycle control. We investigate the role of the fission yeast Cdc14 homologue Clp1/Flp1 in cytokinesis. We find that Clp1/Flp1… Read More

    October 6, 2008