Frequently Asked Questions
What about the availability of compounds?
Our HTS facility has a small-molecule library of over 160,000 selected ‘drug-like’ compounds, primarily from ChemBridge and ChemDiv. We are working to increase our library through the efforts of the Chemical Synthesis Core, as well as other collaborators. Along with the Vanderbilt library, we also house a 100,000 compound library through the Molecular Libraries Screening Center Network (MLSCN) and several smaller libraries 200-2,000 compounds that include the SPECTRUM collection, NIH clinical collection, biolipids, and kinase inhibitor collections. For a list of these libraries, please see our Compound Library page.
What instrumentation is available?
Our instrumentation incorporates the leading edge of biomechanical technology. The crux of our lab technology is comprised of the following:
- BioTek Synergy NEO2
- BioTek Cytation 3
- Molecular Devices High-Content Imaging
- ImageXpress Micro XL
- ImageXpress Micro 4 Confocal
- NANION SynchroPatch
- Labcyte Echo 555 OMICs and 650
- Seahorse XF Pro Analyzer
For a complete list, please see the Instrumentation list in our technology section.
Who is eligible to use the facilities?
All researchers. Please see the Services section for examples offered thus far.
What types of experiments can be performed?
Our facility specializes in cellular-based assays as well as in vitro molecular assays, particularly G-protein coupled receptors (GPCRs), ion channels, disease targets, microbial targets, viral targets, and cancer targets. However, we are able to handle a wide variety of experimental setups, including cytotoxicity, enzyme reactions, immunochemistry, imaging, genomic screening, RNAi screening, and some DMPK assays. For a full discussion of our facility services please reference Assays Design and Assay Targets.
PROJECT ASSISTANCE
PROJECT MANAGEMENT & BILLING
The HTS facility manages and bills projects through iLab.
The first step is to complete a Project Request Form
OTHER ILAB INFORMATION