Ethan Lee, M.D., Ph.D.
Professor of Cell and Developmental Biology
Professor of Pharmacology
- : ethan.lee@vanderbilt.edu
- :
U-4213A MRB-III
Learned Lab
465 21st Avenue South
Nashville, Tennessee - 37232-8240 - : Lab Website
Research Description
Our lab is interested in the basic mechanism of Wnt signal transduction, a pathway that plays critical roles in the early development of multicellular organisms and the maintenance of intestinal stem cells in adults. Misregulated Wnt signaling is often implicated in human diseases such as colorectal cancer. We use biochemistry, chemical biology, cell biology, and developmental biology to study the Wnt pathway.
Our long-term goal of our lab is to leverage the findings from these and other studies to develop effective therapeutics for the treatment of Wnt-driven diseases, including cancers.
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