Vanderbilt Genome Editing Resource

The Vanderbilt Genome Editing Resource (VGER) empowers discovery by creating, preserving, and sharing cutting‑edge genetically engineered mouse and stem cell models. With extensive expertise in CRISPR/Cas9 editing, cryopreservation, and strain development, VGER has supported hundreds of investigators and advanced thousands of research projects. We provide expert consultation and end‑to‑end model‑generation services to accelerate biomedical breakthroughs.

IMPACT

Notable publications

Positive autoregulation of Sox17 is necessary for gallbladder and extrahepatic biliary duct formation.

Trinh LT, Finnel RR, Osipovich AB, Musselman JR, Sampson LL, Wright CVE, Magnuson MA.

Paracrine Hormonal Signals From Islet α-Cells Regulate Microtubule Dynamics in β-Cells to Promote Insulin Secretion in Mouse and Human Islets.

Ho KH, Barmaver SN, Gibson SE, Hu R, Yagan M, Ahmed HK, Balamurugan AN, Jacobson DA, Kaverina I, Gu G.

About VGER

Vanderbilt Genome Editing Resource (VGER), formerly known as the Transgenic Mouse/ES Cell Shared Resource, has been a trusted and invaluable resource specializing in generating unique mouse and iPSC lines, cryopreservation, and rederivation for 30 years. VGER also manages the Vanderbilt Cryopreserved Mouse Repository (VCMR) a unique resource of genetically engineered mouse models donated by Vanderbilt investigators.

If you're interested in partnering with VGER, our team brings years of expertise in creating novel transgenic mouse models and delivering full‑service genome editing for human pluripotent stem cells. We’d be happy to discuss how we can support your research project.

Mission and Oversight

The Vanderbilt Genome Editing Resource (VGER) exists to support scientific discovery by enabling the production and sharing of genetically-altered research models. VGER operates under the oversight of the Vanderbilt Center for Stem Cell Biology, a faculty advisory committee, the Vanderbilt Ingram Cancer Center Shared Resource Oversight Group, and the Center for Basic Sciences.