Fall 2020 VICB Seminars
Fall 2020 Seminar Schedule (via Zoom)
Zoom meeting information will be sent to VICB and CBAS members one week prior to a seminar date. If you have any questions or need more information, please contact Tia Patton at: tia.repscher@vanderbilt.edu
Wednesday, September 2
Peter Seeberger – MAX PLANCK INSTITUTE OF COLLOIDS AND INTERFACES
“Preventing and Fighting Infectious Disease: Carbohydrate Vaccines and Medications in Flow”
12:15 P.M. — 1:15 P.M. Flyer
Recommended Reading for Seeberger Seminar:
Total Synthesis of Polysaccharides by Automated Glycan Assembly
Automated radial synthesis of organic molecules
Imaging single glycans
View zoom video of Dr. Seeberger’s seminar.
Wednesday, September 9
Victor Darley-Usmar – UNIVERSITY OF ALABAMA AT BIRMINGHAM
“A 2020 Perspective on Bioenergetics and Metabolism”
12:15 P.M. — 1:15 P.M. Zoom Flyer
Recommended Reading for Darley-Usmar Seminar:
Bioenergetics and translational metabolism: implications for genetics, physiology and precision medicine
View/download video of Dr. Darlye-Usmar’s seminar.
Wednesday, September 16
Chuan He – UNIVERSITY OF CHICAGO
“RNA Methylation in Gene Expression Regulation”
12:15 P.M. — 1:15 P.M. Zoom Flyer
Recommended Reading for He Seminar:
N6-methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription
Kethoxal-assisted single-stranded DNA sequencing captures global transcription dynamics and enhancer activity in situ
View/Download zoom video of Dr. He’s seminar.
Wednesday, September 23
Chris Chang – UNIVERSITY OF CALIFORNIA-BERKELEY
“Activity-Based Sensing Approaches to Decipher Transition Metal Signaling”
12:15 P.M. — 1:15 P.M. Zoom Flyer
Recommended Reading for Chang Seminar:
Copper regulates rest-activity cycles through the locus coeruleus-norepinephrine system
Copper regulates cyclic-AMP-dependent lipolysis
Activity-based ratiometric FRET probe reveals oncogene-driven changes in labile copper pools induced by altered glutathione metabolism
View/download video of Dr. Chang’s seminar.
Wednesday, September 30
Nevan Krogan & Jacqueline Fabius – UNIVERSITY OF CALIFORNIA-SAN FRANCISCO
“An International Collaborative Effort to Identify Therapeutics for COVID-19”
12:15 P.M. — 1:15 P.M. Zoom Flyer
Recommended Reading for Krogan-Fabius Seminar:
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
The Global Phosphorylation Landscape of SARS-CoV-2 Infection
View/download video of the Krogan-Fabius seminar.
Wednesday, October 7
Gary Gustafson, Medicinal Chemist and Application Specialist, Chemical Abstracts Service (CAS), American Chemical Society
SciFinder-N demonstration
12:15 P.M. — 1:15 P.M. Flyer Via Webex Register Here
View video of Sci-Finder-N Training
Wednesday, October 14
Sara Linse – LUND UNIVERSITY
“Secondary nucleation in amyloid formation”
12:15 P.M. — 1:15 P.M. Zoom Flyer
Recommended Reading for Linse Seminar:
Secondary nucleation in amyloid formation
Ultrastructural evidence for self-replication of Alzheimer-associated Aβ42 amyloid along the sides of fibrils
Kinetic fingerprints differentiate the mechanisms of action of anti-Aβ antibodies
View/download video of the Krogan-Fabius seminar.
Wednesday, November 4
E. James Petersson – UNIVERSITY OF PENNSYLVANIA
“Visualizing alpha-Synuclein in Parkinson’s Disease: From simulations to biochemistry to in vivo imaging”
12:15 P.M. — 1:15 P.M. Zoom
Recommended Reading for Peterrson Seminar:
Identification of a nanomolar affinity α-synuclein fibril imaging probe by ultra-high throughput in silico screening
A Unified De Novo Approach for Predicting the Structures of Ordered and Disordered Proteins
Chemoenzymatic Semisynthesis of Phosphorylated α-Synuclein Enables Identification of a Bidirectional Effect on Fibril Formation
View/download video of the Petersson seminar.
Wednesday, November 11
Scott Thacher – ORPHAGEN PHARMACEUTICALS
“Mining Orphan Nuclear Receptors for New Drugs in Oncology”
12:15 P.M. — 1:15 P.M. Zoom Flyer
Recommended Reading for Peterrson Seminar:
Therapeutic Targets for Adrenocortical Carcinoma in the Genomics Era
Potent, selective and cell penetrant inhibitors of SF-1 by functional uHTS
Retinoic Acid Imprints Gut-Homing Specificity on T Cells
View/download video of the Thacher seminar.
Wednesday, November 18
Thomas Scanlan – OREGON HEALTH & SCIENCE UNIVERSITY
“CNS-Penetrating Thyroid Hormone Agonists for Neurodegenerative Diseases”
12:15 P.M. — 1:15 P.M. Zoom Flyer
- View this Recording of VICB Seminar with Tom Scanlan before November 18th.
- Contact Tia Patton for zoom link and join discussion on November 18th at 12:15 pm.
Recommended Reading for Scanlan Seminar:
Targeting Fatty-Acid Amide Hydrolase with Prodrugs for CNS-Selective Therapy
Myelin repair stimulated by CNS-selective thyroid hormone action
Pharmacological Complementation Remedies an Inborn Error of Lipid Metabolism
Wednesday, December 2
Dorothea Fiedler – LEIBNIZ RESEARCH INSTITUTE FOR MOLECULAR PHARMACOLOGY
“Inositol Pyrophosphates – Multimodal Messengers Interrogated with Chemical Tools”
12:15 P.M. — 1:15 P.M. Zoom
Recommended Reading for Fiedler Seminar:
Harnessing 13C-labeled myo-inositol to interrogate inositol phosphate messengers by NMR
Triplexed Affinity Reagents to Sample the Mammalian Inositol Pyrophosphate Interactome
Features and regulation of non-enzymatic post-translational modifications
View/download video of the Fiedler seminar.