Brian Bachmann, Ph.D.

Brian Bachmann, Ph.D.

Stevenson Professor, Chemistry
Professor, Biochemistry
VICB Associate Director, Molecular Discovery
Director, Vanderbilt Chemistry-Biology Interface Training Program (V-CBI)

Areas of Interest: Infectious Diseases and Immunity; Natural Products; Protein Structure & Function; Synthetic & Medicinal Chemistry; Study and Function of Enzymes; glycobiology

Member: VI4; VICC; VMI; QSBC

The primary mission of the Bachmann Lab is to apply knowledge of the design rules for secondary metabolism at the chemical, biochemical and genetic levels toward the biosynthesis of “non-natural” compounds of high value to biomedical research and the clinic. Key to this program in “synthetic biology” is the dissection of the mechanisms by which life makes bioactive molecules in vivo. The lab is organized according to three interlocking research areas: Biosynthesis, Synthetic Biology, and Discovery. These subgroups each have basic research and applied components and overlap with one another both thematically and methodologically.