Ian Macara, Ph.D.
Chair, Cell and Developmental Biology
Professor - Louise B. McGavock Chair, Cell and Developmental Biology
- : ian.g.macara@Vanderbilt.Edu
- : (615) 875-5565
- :
U-3209 MRBIII
- : More Information/Publications
Areas of Interest: Cancer Biology; Protein Structure & Function; Cell Signaling
Member: VICC; Epithelial Biology Center
Our lab is deeply interested in how epithelial cells make collective decisions and maintain homeostasis; and how these processes are disrupted in response to damage, and during cancer initiation. We use mouse mammary gland and skin, plus human breast organoids, as model epithelial systems. We develop novel transgenic mouse models, genome-wide CRISPR screens, and quantitative, single-molecule imaging modalities to address fundamental questions about epithelial function.