Research News And Discoveries
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Development of a new framework and tool for multi-drug synergy and combination
The Idea Carlos Lopez (Vanderbilt University) Vito Quaranta (Vanderbilt University) Pioneering research from Vanderbilt scientists identifies a measurement system for how well medications work together to help researchers devise new combinations of drugs. It also develops an open-source analysis tool to help speed such discoveries around the world. This research… Read MoreAugust 24, 2021
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An interview with Chuck Sanders, newly elected president of the Protein Society
By Aaron Conley This summer, Chuck Sanders, associate dean for research, professor of biochemistry, and Aileen M. Lange & Annie Mary Lyle Chair in cardiovascular research at Vanderbilt University School of Medicine Basic Sciences, took the helm of the Protein Society as president with a term… Read MoreAugust 23, 2021
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Potential protection from atherosclerosis
Aug. 19, 2021, 11:00 AM by Bill Snyder PON1 (paraoxonase 1), an enzyme associated with high-density lipoprotein (HDL), breaks down lipid peroxides, highly reactive fatty molecules that can damage blood vessels. In this way, PON1 can protect against the development of cardiovascular disease. Numerous studies have observed reduced PON1 enzymatic activity in… Read MoreAugust 20, 2021
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Mosquito larvae are surprisingly complex
THE IDEA Mosquito larvae are surprisingly complex, with a sophisticated sense of smell that enables them to find food, avoid predators and thus become healthy adult mosquitoes with greater ability to transmit disease to humans. While it was previously known that water-dwelling mosquito larvae can taste chemicals in the water,… Read MoreAugust 19, 2021
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Team isolates antibodies that target alphaviruses
Aug. 19, 2021, 10:12 AM by Bill Snyder A multi-institutional team led by researchers at Vanderbilt University Medical Center has isolated monoclonal antibodies that in laboratory and animal studies prevented infection by alphaviruses, including the often-lethal Eastern equine encephalitis virus (EEEV). EEEV, which infects the central nervous system of… Read MoreAugust 19, 2021
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Vega selected as 2021 Vanderbilt Prize Student Scholar
Aug. 11, 2021, 4:10 PM by Bill Snyder Paige Vega, a PhD student in the Department of Cell and Developmental Biology at Vanderbilt University, has been selected as the 2021 Vanderbilt Prize Student Scholar. Paige Vega has been selected as the 2021 Vanderbilt Prize Student Scholar. (photo by Elaine… Read MoreAugust 12, 2021
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Shared antibodies may push COVID-19 variants: VUMC study
Aug. 10, 2021, 9:01 AM by Bill Snyder Researchers at Vanderbilt University Medical Center have found that people recovering from COVID-19 and those vaccinated against the causative virus, SARS-CoV-2, produce identical clones, or groups, of antibody-producing white blood cells. Their discovery, reported this week in the journal Cell… Read MoreAugust 12, 2021
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First-ever gene expression map of an entire nervous system completed; researchers share data to expedite research into genetic defects affecting the brain
THE IDEA Research Assistant Professor Seth Taylor and Professor David Miller, both in Vanderbilt University’s Department of Cell and Developmental Biology, have established a gene expression atlas for the nervous system of the nematode C. elegans, along with… Read MoreJuly 30, 2021
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Researchers derive new cancer therapies to decrease the risk of heart damage
by Skylar Cuevas THE IDEA With modern-day cancer therapeutics presenting adverse side effects to heart health, scientists are studying methods to attack cancer cells without the risk of damaging the heart. Researchers Steven Townsend, associate professor of chemistry, and Neil Osheroff, John… Read MoreJuly 29, 2021
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Research Snapshot: Novel discovery describes the mechanisms of wound detection in the body
THE IDEA A new study from Vanderbilt University researchers has established a novel way to understand how the body discovers and responds to wounds. The research was led by graduate student James O’Connor and Professor Andrea Page-McCaw in the Department of Cell… Read MoreJuly 28, 2021