Research, News & Discoveries

Meet Jo Ann Byl, senior research specialist in the School of Medicine Basic Sciences Department of Biochemistry. Read More

Subtomogram averaging, a process similar to single particle analysis in cryo-electron microscopy, is used to reconstruct a 3D volume of a sample from preprocessed tilt-series data for accurate downstream analysis. While many individual preprocessing packages exist, they utilize different design philosophies, inputs, outputs, and file formats, making construction of a complete data pipeline difficult. TOMOMAN (TOMOgram MANager), an extensive MATLAB-based package developed by the Wan lab, aims to address this issue. Read More

A leading chemical biologist working on ribosomally synthesized and post-translationally modified peptides, Doug Mitchell has joined the School of Medicine Basic Sciences as the William Kelly Warren Sr. Professor of Biochemistry and director of the Vanderbilt Institute for Chemical Biology. He also has been named professor of chemistry. Read More

Congratulations to our School of Medicine Basic Sciences members who were promoted or received new appointments between October and December 2024. These individuals significantly enrich our pursuit of pathbreaking research and contribute to the growth and success of our school.  Read More

Whitehead Institute Professor of Biology David Bartel will present the Vanderbilt School of Medicine Basic Sciences Apex Lecture on Jan. 15, 2025. Read More

Phase I clinical trial of drug was successfully completed at the Warren Center for Neuroscience Drug Discovery, with promise to treat Alzheimer’s and other neurodegenerative diseases. The compound, named VU319, is the first Vanderbilt end-to-end drug discovery effort related to memory loss, starting from the earliest basic science research through human clinical trials. Read More

As 2024 comes to a close, we take a look back at the accomplishments and contributions to science and society made by School of Medicine Basic Sciences community members throughout the past year. The efforts of our faculty, trainees, staff, and collaborators have resulted pioneering discoveries that tangibly benefit society. Read More

Lori Rudolph-Owen, an accomplished figure in the biotechnology industry and a Vanderbilt University School of Medicine Basic Sciences alum, shared her insights on career progression and drug development on Oct. 3 as part of BRET’s Ph.D. Career Stories, a series focused on various alums and their professions. Read More

Doug Kojetin, associate professor of biochemistry, and a collaborator from the Guangzhou Laboratory, use NMR and crystallography to elucidate the binding pose of GW9662 and T0070907 cobound with synthetic ligands for the first time. Read More

Sonja Fulmer, a graduate of Chemical and Physical Biology Program who is now the deputy director of the FDA’s Digital Health Center of Excellence, sat down with us to discuss her experience studying basic science at Vanderbilt and how it played a role in her successful career. Read More