Biochemistry

Brandt Eichman and Walter Chazin, professors of biochemistry, worked together to provide a better understanding of how exactly DNA replication is initiated. Their work will influence novel small molecule modifier designs that may serve as tools for detailed studies of DNA replication in cells and eventual therapies. Read More

By putting one foot in front of another, these trailblazers have changed Vanderbilt—and the world—with their dedication to basic research and breaking down barriers for themselves and others. Read More

Bruce Carter, Lisa Monteggia, Richard O’Brien, Andrea Page-McCaw, and Kevin Schey have been named endowed chairs, the highest academic award that Vanderbilt can give to a faculty member. Read More

The World Health Organization ranks antimicrobial resistance as one of the top ten global health risks. Vanderbilt researchers led by Houra Merrikh identified the first anti-evolution compound that targets AMR during treatment of infections with antibiotics. Read More

The lab of Professor of Biochemistry Fred Guengerich has proposed a paradigm shift in the understanding of a critical chemical reaction involved in sterol biosynthesis. Read More

For bichemist Fred Guengerich, the story of his 50-plus years in science can be told through his 98 semesters on Vanderbilt University’s faculty; the 22 graduate students and 141 postdoctoral fellows and visiting scientists he has mentored; the 768 primary research papers, 324 invited reviews and chapters, and 138 book chapters and published proceedings he has authored; and the 125,316 of times he has been cited. But even those numbers don’t tell the whole story. Read More

Combining deep mutagenesis and cryo-EM reveals new conformational state of a protein responsible for high-speed DNA replication. The research builds on growing theories of molecular evolution. Read More

High school student Benjamin Gordon, former Marnett lab intern, has been named a top scholar in the Regeneron Science Talent Search 2024, the oldest science and math competition for high school seniors in the U.S. Read More

We extend congratulations to our many community members who were recently promoted or received new appointments. These individuals significantly enrich our pursuit of pathbreaking research and contribute to the growth and success of our school. Read More

An international collaboration led by Vanderbilt researchers has identified a key component in lesions associated with age-related macular degeneration (AMD), a leading cause of blindness in older adults. Read More