Cameron Cohen

Acanthamoeba can cause diseases blinding keratitis, an infection of the eye, or granulomatous amebic encephalitis, a generally fatal infection of the brain and spinal cord. Antifungals that target the biosynthesis of fungal sterols, such as ergosterol, are often used as treatment, but the Acanthamoeba ergosterol biosynthetic pathway has been shown to differ significantly from that found in fungi. Read More

Cryo-ET suffers from the “missing wedge” problem: as samples become more tilted, their thickness at the extremes is increased and sample penetration decreases. William Wan and collaborators describe the creation of a new subtomogram averaging package called STOPGAP. Read More

By Leah Mann The labs of Lauren Jackson, associate professor of biological sciences and biochemistry, and Todd Graham, Stevenson Professor of Biological Sciences at the College of Arts and Science and professor of cell and developmental biology, recently published a study in the Journal of Cell Biology… Read More