Diffuse Scattering

Started in June 2025, a new collaborative science project called diffUSE involving Vanderbilt University, Cornell University, and the University of California, San Francisco, could be the next watershed moment. The $5 million, three-year project led by the Astera Institute will advance our understanding of protein motion. Using diffuse scattering, an overlooked signal measured by X-ray crystallography, the project will determine how protein dynamics are characterized, leading to a new paradigm in dynamic structural biology. Read More