Doug Mitchell

In the hunt for new therapeutics for cancer and infectious diseases, lasso peptides prove to be a catch. Their knot-like structures afford these molecules high stability and diverse biological activities, making them a promising avenue for new therapeutics. To better unleash their clinical potential, a team co-led by Doug Mitchell developed LassoESM, a new large language model for predicting lasso peptide properties. Read More

Vanderbilt researchers probe the mysteries of an enzyme that could be used as a tool in basic research and medicinal chemistry. Read More

The Vanderbilt Institute of Chemical Biology held its annual Student Research Symposium on Aug. 1, drawing a record number of registrants and poster presenters. Organized by the Chemical Biology Association of Students, the event showcased cutting-edge research, interdisciplinary collaborations, and exceptional contributions from both trainees and faculty. Read More

A leading chemical biologist working on ribosomally synthesized and post-translationally modified peptides, Doug Mitchell has joined the School of Medicine Basic Sciences as the William Kelly Warren Sr. Professor of Biochemistry and director of the Vanderbilt Institute for Chemical Biology. He also has been named professor of chemistry. Read More

A leading chemical biologist working on ribosomally synthesized and post-translationally modified peptides, Doug Mitchell has joined the School of Medicine Basic Sciences as the William Kelly Warren Sr. Professor of Biochemistry and director of the Vanderbilt Institute for Chemical Biology. He also has been named professor of chemistry. Read More