Epigenetics

Recent work from a coalition of Vanderbilt labs has found clear distinctions in insulin-secreting β-cell subtypes and drawn a connection between certain subtypes and a higher risk of diabetes. Read More

A recent paper from the lab of Emily Hodges looks at how two types of epigenetic changes act together but on different time scales to affect gene expression during cell differentiation. Read More

The labs of Emily Hodges, assistant professor of biochemistry, and Tony Capra, associate professor of epidemiology and biostatistics at the University of California, San Francisco, have devised a method to separate the relative contributions of cis vs. trans regulatory mechanisms to gene regulatory divergence between species. Read More

William Tansey, professor of cell and developmental biology and biochemistry and co-leader of the Vanderbilt-Ingram Cancer Center Genome Maintenance Program, gives us a bird’s-eye view of epigenetics and some of Vanderbilt’s research contributions to the space. Read More

Research led by Emily Hodges, assistant professor of biochemistry, first-author Lindsey Guerin, a graduate student in the Hodges lab, and Kelly Barnett, a recent graduate of the Hodges lab, developed and tested a new method called ATAC-Me, which profiles multiple epigenetic features, including DNA methylation, simultaneously from a single DNA… Read More