Lung

Driven by personal loss, a graduate student and his mentors unveil the mysteries of CFTR mutations, seeking to unlock new treatments for cystic fibrosis patients who currently resist available drugs. Read More

A study of a unique spatial map of gene expression in 1.6 million cells from the lungs of 35 people with pulmonary fibrosis revealed a discovery that could eventually change how early PF can be detected. Some lung tissue in these patients shows signs of the disease before significant structural remodeling of the tissue occurs. Read More

A research grant to study lung and cerebral organoids will yield insights into the sensitivity of lung and brain tumors to commercially available antibody-drug conjugate payloads. The OVPRI Industry Collaborations group facilitated the collaboration. Read More

Small cell lung cancer (SCLC) is a highly aggressive, particularly deadly form of cancer noted for its early metastasis and resistance to therapy. One explanation for these traits is that SCLC is usually composed of heterogeneous cell populations, most often including cells with neuroendocrine (NE) traits and those with mesenchymal-like… Read More