Neuroscience

What makes these results exceptional isn’t just the compounds themselves, it’s what they represent: the value of translational research grounded in real-world therapeutic goals. The partners chose to release these best-in-class tool compounds to the scientific community to accelerate further discovery. Read More

Major depression is one of the most common mental disorders in the U.S. Approximately 7% (17.3 million) of American adults had at least one major depressive episode in 2017. Roughly 10 percent of the U.S. population is afflicted with major depressive disorder at any… Read More

What makes these results exceptional isn’t just the compounds themselves, it’s what they represent: the value of translational research grounded in real-world therapeutic goals. The partners chose to release these best-in-class tool compounds to the scientific community to accelerate further discovery. Read More

In this episode of Quantum Potential, Craig Lindsley, William K. Warren, Jr. Professor of Medicine, University Distinguished Professor of Biochemistry, Chemistry and Pharmacology and executive director of the Warren Center for Neuroscience Drug Discovery, joins Provost C. Cybele Raver to discuss transformative research exploring how subtle tweaks to brain chemistry could change the way we treat neurodegenerative diseases and chronic pain. Lindsley shares how academic-industry collaborations drive innovation in drug discovery and highlights how Vanderbilt’s scientific workflow is enabling the broader research community to build on its breakthroughs. Read More

For the nearly 30 percent of major depressive disorder patients who are resistant to treatment, ketamine provides some amount of normalcy, but it requires frequent treatment and can have side effects. Vanderbilt researchers now show in proof-of-concept experiments that it may be possible to extend ketamine’s antidepressant effect from about a week to up to two months. Read More

The Vanderbilt Brain Institute’s annual Brain Blast event, held March 26 at the downtown Nashville Public Library, celebrated 25 years of discovery with a day of hands-on neuroscience activities for K–8 students and families. Read More

Anne Taylor, PhD'23, sat down with us to discuss her experience studying basic science at Vanderbilt and how it played a role in her career. Taylor is now a fellow at the Center for Opioid Research, Education & Outreach at the Auburn University Harrison College of Pharmacy. Read More

Researchers from the lab of Richard Simerly have uncovered the first example of activity-dependent development of hypothalamic neural circuitry. The work also suggests a novel role for the hunger hormone leptin in specifying the development of neural circuits involved in autonomic regulation and food intake. Read More

Calipari wins award for transforming scientists’ understanding of how behavioral circuits are dysregulated by long-term drug use and for her commitment to train and support the next generation of addiction scientists. Read More

Led by Terunaga Nakagawa, an international collaboration describes for the first time the fundamental mechanism underpinning cellular processes that lead to learning and memory. Read More