School Of Medicine Basic Sciences
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School of Medicine Basic Sciences Staff Spotlight: David Baughman
Meet David Baughman, the research program manager for the Vanderbilt Institute of Chemical Biology. Read MoreMarch 13, 2025
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Vanderbilt researchers identify potential drug combinations to improve breast cancer treatment
Triple-negative breast cancer accounts for 10 percent of breast cancer cases in the U.S. annually. As T-cells that normally kill cancer cells often become exhausted and stop, Vanderbilt pharmacologists are seeking chemotherapy or targeted therapy approaches that can enhance the T-cell killing of cancer cells. Read MoreMarch 10, 2025
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Study uncovers significant differences in a dietary supplement’s key ingredient
New research by Vanderbilt pharmacologists has uncovered inconsistencies in the active ingredient levels of a dietary supplement often referred to as corydalis. The work, published in Frontiers in Pharmacology, highlights concerns regarding the efficacy and authenticity of these widely used supplements. Read MoreMarch 3, 2025
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UC San Diego Professor and Chair of Neurobiology Ryan Hibbs to deliver Apex Lecture on March 27
Ryan Hibbs, professor and chair of neurobiology at the University of California, San Diego, will present the Vanderbilt School of Medicine Basic Sciences Apex Lecture on March 27, 2025. Read MoreMarch 3, 2025
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Vanderbilt biomedical research paves the way for ‘hypoallergen’ treatments against peanut allergies
Peanuts cause the highest number of food allergy–related deaths in the U.S. Basic scientists at Vanderbilt uncover how the allergy works and suggest new potential treatments. Read MoreFebruary 24, 2025
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Basic science alums give a glimpse inside the world of medical science liaisons during BRET’s career series
The Office of Biomedical Research Education and Training hosted a Ph.D. Career Stories presentation focused on medical affairs and the role of medical science liaisons. The event featured Vanderbilt University alums Casey (Butrico) Hatfield and Todd Townsend, who provided insights into their career paths, responsibilities, and experiences as medical science liaisons. Read MoreFebruary 20, 2025
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Vanderbilt and Northwestern labs discover new mechanisms that cause irregular heartbeat
Vanderbilt and Northwestern University researchers characterized a group of KCNQ1 variants probe their role in a common heart disorder called LQTS. They found that there are five classes of mutations that act through independent mechanisms, suggesting that a more tailored/personalized treatment approach could be beneficial for LQTS patients. Read MoreFebruary 18, 2025
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Does your liver know what time it is?
Physician-scientist Mitch Lazar delivered a School of Medicine Basic Sciences Apex Lecture on Feb. 11 about nuclear receptors and the circadian regulation of metabolism. Read MoreFebruary 18, 2025
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Greater than the sum of its parts: the role of VARP-SNX27 binding in endosomal “supercomplex” formation
The lab of Lauren Jackson provides the first evidence of an endosomal “supercomplex” and reveals a vital role for VARP in mediating coat assembly in a recent paper published in Science Advances. Read MoreFebruary 17, 2025
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Molecular biologist David Bartel delivers Apex Lecture on target-directed microRNA degradation
Renowned Massachusetts Institute of Technology molecular biologist David Bartel delivered a School of Medicine Basic Sciences Apex Lecture on Jan. 15 about the regulation of mRNA translation and decay. Read MoreFebruary 6, 2025