Wenbiao Chen

By Leah Mann Wenbiao Chen, Ph.D. The lab of Wenbiao Chen, associate professor of molecular physiology and biophysics, identified a signaling pathway for hyperaminoacidemia-induced alpha cell proliferation. Hyperaminoacidemia, or an excess of amino acids in the bloodstream, occurs when the function of glucagon, a pancreatic hormone that raises glucose levels… Read More

By Leah Mann Wenbiao Chen, Ph.D. The labs of Wenbiao Chen, associate professor of molecular physiology and biophysics, and Irina Kaverina, professor of cell and development biology, recently published a study in Molecular Metabolism focused on detecting genes that regulate insulin secretion. The authors demonstrated a new… Read More

Obesity and overnutrition increase the risk of Type 2 diabetes through several mechanisms. One of these is through loss of the insulin-producing beta cells of the pancreatic islet.  Wenbiao Chen, PhD, and colleagues previously have shown that overnutrition stressed the endoplasmic reticulum, the part of the beta… Read More