Ben Park
Vanderbilt-Ingram Cancer Center (VICC)
Program in Cancer Biology
VICC Breast Cancer Research Program
Precision Oncology
Department of Medicine
Division of Hematology and Oncology
The Park Lab uses genetic approaches to identify, validate and develop new targets for therapy as well as diagnostic tests to help guide clinical decision making for breast cancer. Using human somatic cell gene editing, we create and exploit isogenic cell lines to achieve these aims. Our goal is to then translate these laboratory findings for clinical trials and patient benefit and have accomplished this using plasma tumor cell-free DNA as a biomarker for residual tumor burden.
The Park Lab uses genetic approaches to identify, validate and develop new targets for therapy as well as diagnostic tests to help guide clinical decision making for breast cancer. Using human somatic cell gene editing, we create and exploit isogenic cell lines to achieve these aims. Our goal is to then translate these laboratory findings for clinical trials and patient benefit and have accomplished this using plasma tumor cell-free DNA as a biomarker for residual tumor burden.
Keywords: breast cancer , genetics , genome editing , molecular targets , therapy , liquid biopsy
Research Area: Cancer Biology