Andrea Page-McCaw
Program in Developmental Biology (PDB)
Vanderbilt Center for Matrix Biology (VCMB)
Department of Cell and Developmental Biology (CDB)
Program in Cancer Biology
Vanderbilt-Ingram Cancer Center (VICC)
Our lab is interested in basic science questions about how tissues are formed and how they are repaired. Current projects center on how cells detect a nearby wound, basement membrane repair, and extracellular signaling controlling stem cell functions. Most of our experiments are performed in the fruitfly Drosophila melanogaster whose biology is surprisingly similar to our own.
Epithelial cells respond immediately to a wound (at 0 sec) by increasing intracellular calcium (imaged with GCaMP6m).
Our lab is interested in basic science questions about how tissues are formed and how they are repaired. Current projects center on how cells detect a nearby wound, basement membrane repair, and extracellular signaling controlling stem cell functions. Most of our experiments are performed in the fruitfly Drosophila melanogaster whose biology is surprisingly similar to our own.
Keywords: Developmental Biology , Genetics , Cell Signaling , Extracellular Matrix , Drosophila , Wound healing
Research Area: Stem Cell Biology & Regeneration , Cancer Biology , Cell Signaling , Developmental Biology