Angela Jefferson
Vanderbilt Brain Institute (VBI)
Vanderbilt Genetics Institute (VGI)
Department of Neurology
The Vanderbilt Memory & Alzheimer’s Center is an interdisciplinary research program advancing our understanding of risk factors, early diagnostic markers, and prevention and treatment methods for memory loss and abnormal cognitive aging, including Alzheimer’s disease, cerebral small vessel disease, and neurodegeneration in older adults. Our innovative research portfolio includes initiatives (1) examining vascular health intersections with Alzheimer’s disease and neurodegeneration to identify risk factors and prevention targets, (2) identifying tools for early detection of unhealthy cognitive aging, and (3) elucidating factors underlying resilience to the clinical manifestation of Alzheimer’s disease. Trainees gain knowledge and skills working with a comprehensive, longitudinal study of older adults, including but not limited to multi-modal neuroimaging, cardiac imaging, blood and cerebrospinal fluid biomarkers, genomics and proteomics, neuropsychological assessment, and lifestyle factors.
The Vanderbilt Memory & Alzheimer’s Center is an interdisciplinary research program advancing our understanding of risk factors, early diagnostic markers, and prevention and treatment methods for memory loss and abnormal cognitive aging, including Alzheimer’s disease, cerebral small vessel disease, and neurodegeneration in older adults. Our innovative research portfolio includes initiatives (1) examining vascular health intersections with Alzheimer’s disease and neurodegeneration to identify risk factors and prevention targets, (2) identifying tools for early detection of unhealthy cognitive aging, and (3) elucidating factors underlying resilience to the clinical manifestation of Alzheimer’s disease. Trainees gain knowledge and skills working with a comprehensive, longitudinal study of older adults, including but not limited to multi-modal neuroimaging, cardiac imaging, blood and cerebrospinal fluid biomarkers, genomics and proteomics, neuropsychological assessment, and lifestyle factors.
Keywords: Alzheimer's disease , cerebral small vessel disease , neurodegeneration , memory loss , clinical neuroscience , aging
Research Area: Computational and Systems Biology , Imaging , Genomics , Cardiovascular Biology , Vascular Biology , Neurodegeneration and Neuroinflamation , Proteomics/Metabolomics