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Christine Lovly

Department of Medicine
Division of Hematology and Oncology
Vanderbilt-Ingram Cancer Center (VICC)
Translational Research and Interventional Oncology Program
U54 Cancer Systems Biology Consortia


Research in the Lovly lab focuses on two major themes: 1) stratification of lung tumors into clinically relevant molecular subsets, with a particular interest in those tumors which harbor EGFR mutations, ALK gene rearrangements, and small cell lung cancer and 2) determination of the molecular mechanisms leading to primary and acquired resistance to anti-cancer therapies. We work from the ground up to understand the key genetic and molecular events contributing to the development and progression of lung cancer, utilizing a variety of techniques, including genomic and proteomic studies, in silico modeling, and high throughput / high content imaging screens in order to obtain deep mechanistic insights into these events. Our entire team is excited to welcome new members and share our passion for translational lung cancer research!

Research in the Lovly lab focuses on two major themes: 1) stratification of lung tumors into clinically relevant molecular subsets, with a particular interest in those tumors which harbor EGFR mutations, ALK gene rearrangements, and small cell lung cancer and 2) determination of the molecular mechanisms leading to primary and acquired resistance to anti-cancer therapies. We work from the ground up to understand the key genetic and molecular events contributing to the development and progression of lung cancer, utilizing a variety of techniques, including genomic and proteomic studies, in silico modeling, and high throughput / high content imaging screens in order to obtain deep mechanistic insights into these events. Our entire team is excited to welcome new members and share our passion for translational lung cancer research!

Keywords: Translational cancer research , Lung Cancer , Drug resistance , Genomics , Clinical trials

Research Area: Genomics , Proteomics/Metabolomics