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F. Peter Guengerich

Department of Biochemistry
Training Program in Molecular Toxicology


The Guengerich laboratory is interested in the enzymes involved in the activation and processing of xenobiotic chemicals (i.e., those not normally found in the body, such as drugs and carcinogens), as well as steroids and vitamins. The work is focused on the enzymology of two major groups of enzymes, cytochromes P450 and DNA polymerases.

The Guengerich laboratory is interested in the enzymes involved in the activation and processing of xenobiotic chemicals (i.e., those not normally found in the body, such as drugs and carcinogens), as well as steroids and vitamins. The work is focused on the enzymology of two major groups of enzymes, cytochromes P450 and DNA polymerases.

Keywords: Cytochrome P450 , DNA polymerases , Enzyme kinetics , Mass spectrometry , Proteomics , Metabolomics

Research Area: Diabetes, Obesity, Metabolism , Chemical Biology , Proteomics/Metabolomics