Jin Chen
Program in Cancer Biology
Vanderbilt-Ingram Cancer Center (VICC)
Department of Medicine
VA Medical Center
Current focus of our lab is to investigate how receptor tyrosine kinase signaling in tumor cells affects glutamine metabolism and tumor immunity. We also study how tumor blood vessel normalization affect anti-tumor immune cells recruitment and activation.
Current focus of our lab is to investigate how receptor tyrosine kinase signaling in tumor cells affects glutamine metabolism and tumor immunity. We also study how tumor blood vessel normalization affect anti-tumor immune cells recruitment and activation.
Keywords: tumor immunity , glutamine metabolism , tumor blood vessel normalization , EphA2 receptor tyrosine kinase , mTOR signaling , develop mTORC2-specific inhibitor
Research Area: Drug Design , Cancer Biology , Cancer Immunology , Cell Signaling , Developmental Biology