John Stafford
Vanderbilt Diabetes Research and Training Center (DRTC)
Vanderbilt Digestive Diseases Research Center (VDDRC)
Vanderbilt Mouse Metabolic Phenotyping Center (VMMPC)
Our lab aims to define and target pathways that give rise to cardiovascular disease with obesity and diabetes. We study liver metabolism in vivo, how obesity alters lipoprotein metabolism, and male female differences in metabolic and cardiovascular risk. We use cutting-edge tracer approaches to define glucose and lipid metabolism. We do functional studies of HDL and its ability to protect from heart disease. We use mouse and human studies.
Our lab aims to define and target pathways that give rise to cardiovascular disease with obesity and diabetes. We study liver metabolism in vivo, how obesity alters lipoprotein metabolism, and male female differences in metabolic and cardiovascular risk. We use cutting-edge tracer approaches to define glucose and lipid metabolism. We do functional studies of HDL and its ability to protect from heart disease. We use mouse and human studies.
Keywords: Obesity , diabetes , estrogen , hyperinsulinemic-euglycemic clamp , liver , HDL
Research Area: Diabetes, Obesity, Metabolism , Cardiovascular Biology