Katty Kang
The Kang Laboratory is interested in understanding the role of GABAergic signaling in disease conditions as well as in normal brain development. Currently, lab staff members are investigating the molecular pathophysiology of genetic variations/mutations in GABAA receptor subunits and GABA transporter 1, two major components of GABAergic signaling and common pediatric disorders: epilepsy, autism and intellectual disability. The goal is to understand how a single nucleotide change like a mutation could define the whole life of a child and identify the most effective precision treatments for those who have these disorders in order to improve their life outcome.
The Kang Laboratory is interested in understanding the role of GABAergic signaling in disease conditions as well as in normal brain development. Currently, lab staff members are investigating the molecular pathophysiology of genetic variations/mutations in GABAA receptor subunits and GABA transporter 1, two major components of GABAergic signaling and common pediatric disorders: epilepsy, autism and intellectual disability. The goal is to understand how a single nucleotide change like a mutation could define the whole life of a child and identify the most effective precision treatments for those who have these disorders in order to improve their life outcome.
Keywords: GABAergic signaling , Epilepsy , autism , intellectual disability , precision treatment , brain development
Research Area: Molecular Pathology , Cell Signaling , Developmental Neuroscience