Mark de Caestecker
Vanderbilt Center for Kidney Disease
Mass Spectrometry Research Center
I am a physician-scientist. My research focuses on development and testing of novel therapeutics to enhance the regenerative capacity of kidneys after injury (using a Zebrafish screen and mouse models of injury), as well as the analysis of retinoic acid signaling and macrophage function after kidney injury. We have been continuously funded since 2002, and have recently been successful in obtaining a new DOD drug discovery grant to identify new therapeutic approaches to prevent chronic kidney disease progression after acute kidney injury (AKI). I am committed to teaching and mentoring in biomedical sciences. I have trained 6 PhD graduate students, 1 MD PhD and 1 Master’s student in my lab since 2000. I am a member of the Department of Cell and Developmental Biology Graduate Steering Committee and Director of the Vanderbilt Program in Molecular Medicine (VPMM). I am research area director for bench research immersion projects, which is a requirement for 3rd year medical students at Vanderbilt University Medical School. I am also Director of the Education and Outreach Program for the Vanderbilt Center for Kidney Disease, Director of the Summer Research Training Program (SRTP) in Kidney Disease, and the Vanderbilt Mouse Kidney Injury Workshop.
I am a physician-scientist. My research focuses on development and testing of novel therapeutics to enhance the regenerative capacity of kidneys after injury (using a Zebrafish screen and mouse models of injury), as well as the analysis of retinoic acid signaling and macrophage function after kidney injury. We have been continuously funded since 2002, and have recently been successful in obtaining a new DOD drug discovery grant to identify new therapeutic approaches to prevent chronic kidney disease progression after acute kidney injury (AKI). I am committed to teaching and mentoring in biomedical sciences. I have trained 6 PhD graduate students, 1 MD PhD and 1 Master’s student in my lab since 2000. I am a member of the Department of Cell and Developmental Biology Graduate Steering Committee and Director of the Vanderbilt Program in Molecular Medicine (VPMM). I am research area director for bench research immersion projects, which is a requirement for 3rd year medical students at Vanderbilt University Medical School. I am also Director of the Education and Outreach Program for the Vanderbilt Center for Kidney Disease, Director of the Summer Research Training Program (SRTP) in Kidney Disease, and the Vanderbilt Mouse Kidney Injury Workshop.
Keywords: Kidney , Regeneration , Drug Discovery , Retinoic acid signaling , Macrophages , Injury and repair
Research Area: Drug Design , Stem Cell Biology & Regeneration , Cell Signaling , Proteomics/Metabolomics